Open cloud cells can be described in ideal form as connected clouds that surround spots of isolated clear skies in their centers. This cloud pattern is typically associated with marine stratocumulus (MSc) that form in the oceanic boundary layer. However, it can form in deeper convective clouds as well. Here, we focus on deep-open-cells (with tops reaching up to ~5–7 km) that form in the post-frontal regions of winter Mediterranean cyclones, and examine their properties and evolution. Using a Lagrangian analysis of satellite data, we show that deep-open-cells have a larger equivalent diameter (~58 ± 18 km) and oscillate with a longer periodicity (~3.5 ± 1 h) compared to shallow MSc. A numerical simulation of one Cyprus low event reveals that precipitation-generated convergence and divergence dynamic patterns are the main driver of the open cells’ organization and oscillations. Thus, our findings generalize the mechanism attributed to the behavior of shallow marine cells to deeper convective systems.