A Clinical Profile and Immediate Outcome of Acute Glomerulonephritis (AGN) in Hospitalized Children

Bhuiyan, A. N. M. Shahidul Islam; Alam, Zahangir; Hasan, Khondaker Zahirul; Zaman, Mostafa; Zakaria,

doi:10.11648/j.ajp.20200604.20

Cited by 3 publications

(3 citation statements)

References 8 publications

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“…In the present study 12 out of 30 children had atypical presentations which is similar to studies done by Kuralvanan Gunasekaran et al (9) and Islam Bhuiyan et al (10). Kapil Bhalla et al (1) showed higher incidence of Acute kidney injury and congestive cardiac failure in children with AGN.…”

Section: Table -2: Clinical Featuressupporting

confidence: 90%

A Study on Clinical Presentations and Laboratory Profile of Acute Glomerulonephritis in Children Admitted in a Tertiary Care Hospital

Manikyamba¹,

Satyavani²,

Madhavi³

et al. 2022

Global Journal for Research Analysis

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Introduction: Acute glomerulonephritis is the most common reversible cause of kidney disease in children. Although most common presentations are oedema, hypertension, haematuria and oliguria, glomerulonephritis may manifest with atypical features. Aims and objectives: The aim of the study was to evaluate the frequency of various clinical manifestations of glomerulonephritis and to identify various abnormalities in laboratory prole in children with glomerulonephritis. Materials and methods: 30 children admitted in paediatric department, King George Hospital, Visakhapatnam with clinical features of glomerulonephritis were enrolled into the study . Data on clinical features, laboratory parameters and outcome was recorded. Results: Males were more commonly affected. Majority were in the age group of 9-12 years. Most common presentation was facial pufness. Atypical presentations were observed in 40% cases. Anaemia was observed in 50% cases. Hypertension was seen in 56% of cases. PSGN was commonest cause of AGN. Hypocomplementemia was seen in 80% cases. Conclusion: Even though most children with acute glomerulonephritis present with common clinical features, early identication of atypical presentations of acute glomerulonephritis should be emphasised as their prompt recognition can lead to reduction in mortality.

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Section: Table -2: Clinical Featuressupporting

confidence: 90%

A Study on Clinical Presentations and Laboratory Profile of Acute Glomerulonephritis in Children Admitted in a Tertiary Care Hospital

Manikyamba¹,

Satyavani²,

Madhavi³

et al. 2022

Global Journal for Research Analysis

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“…Approximately 62.4% of patients had reactive ASO titers, but this rate was lower than that in other studies, such as Odisha (78.1%), and higher than that in a study performed in Bangladesh (52.6%) (19,20). All patients were treated with furosemide, additional antihypertensive drugs such as nifedipine (29.8%), hydralazine (18.4%), enalapril (1.4%) and both enalapril and nifedipine (2.8%).…”

Section: Discussioncontrasting

confidence: 57%

Treatment and clinical outcomes of acute glomerulonephritis among children admitted to the pediatric ward, Asella Teaching and Referral Hospital, Arsi, Ethiopia

Demssie,

Abay,

Derso

2023

Preprint

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Background Acute glomerulonephritis is an acute kidney injury syndrome characterized by the sudden onset of edema and new-onset or worsening hypertension. It is common in school-aged children and typically presents with hematuria, edema, oliguria and varying degrees of renal insufficiency. This problem is particularly important in developing countries. Therefore, this study aimed to assess the treatment and clinical outcomes of AG among children admitted to the pediatric ward in Asella Teaching and Referral Hospital, Ethiopia. Methods A retrospective cross-sectional study design was conducted at the Asella Teaching and Referral Hospital pediatrics ward from September 2017 to June 2021. A simple random sampling technique was applied to select 282 study participants. Modified questionnaires based on a previous study were used to collect the data and then entered into Epi-info version 7.2.1.0 and exported to SPSS version 23 for further analysis. Result A total of two hundred eighty-two records of children diagnosed with acute glomerulonephritis were included in this study. The age range of the participating patients was 2 to 14 years. More affected patients were male. The most affected age group was between 6 and 10 years (55.3%). The most common clinical manifestation was facial edema (100%), and leg edema was 90.1%. The complications were hyperkalemia (10.6%), heart failure (9.9%) and anemia (9.2%). A total of 131 (92.9%) patients improved and were discharged within two weeks (positive outcome). Conclusion The highly affected age group was between 6 and 10 years, and most of the patients were admitted with different complications. Timely and proper intervention is necessary, and long-term follow-up should be performed in every patient.

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“…Hematuria was found in 92.3% of patients, hematuria affected the length of stay and 6% of cases is persisted until the patient was discharged. 9 ASTO titers were recorded to increase by 42.9% in a study in Pakistan.…”

Section: Discussionmentioning

confidence: 94%

Clinical picture of acute post-streptococcal glomerulonephritis in children at Ruteng hospital

Ongo,

Putri,

Naur

2023

Int J Res Med Sci

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Background: Acute post-streptococcal glomerulonephritis (PSGN) is the main cause of acute nephritis in children, globally reaches more than 470,000 cases per year, 97% of which occur in developing countries. Sublinical cases are 4 times more common than symptomatic, so reports on the incidence of acute PSGN are very limited. Methods: This study used a descriptive retrospective method from medical records at RSUD Ruteng from January to June 2023. Data were analyzed using the statistical package for the social sciences (SSPS) 22 program. Results: Results of the study were obtained as 37 pediatric patients with acute PSGN. The patients age ranged 4-17 years with an average 9 years, 51.4% women and 48.6% men. Most cases occur after respiratory tract infections (75.7%). Symptoms of edema and hypertension (89.2% stage I and 10.8% stage II) was found in all patients and become the reason why patients come. Patients experienced macroscopic hematuria 16.2%. The laboratory test showed 100% microscopic hematuria, proteinuria in 72.1% and ASTO titer increased by more than 200 IU in all patients. Eleven patients with complications, acute renal failure (24.3%), hypertension encephalopathy (5.4%) and 1 patient with pulmonary edema. The average length of stay is 8 days (3-22 days). Conclusions: The incidence of acute PSGN at RSUD Ruteng within 6 months is quite high. Acute PSGN in children causes severe complicationsand longer treatment. The prevention is needed to care about the importance of clean and healthy living behavior.

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A Clinical Profile and Immediate Outcome of Acute Glomerulonephritis (AGN) in Hospitalized Children

Cited by 3 publications

References 8 publications

A Study on Clinical Presentations and Laboratory Profile of Acute Glomerulonephritis in Children Admitted in a Tertiary Care Hospital

A Study on Clinical Presentations and Laboratory Profile of Acute Glomerulonephritis in Children Admitted in a Tertiary Care Hospital

Treatment and clinical outcomes of acute glomerulonephritis among children admitted to the pediatric ward, Asella Teaching and Referral Hospital, Arsi, Ethiopia

Clinical picture of acute post-streptococcal glomerulonephritis in children at Ruteng hospital

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