A clinical study of dermatoses in diabetes to establish its markers

Abstract

Background:Cutaneous manifestations of diabetes mellitus generally appear subsequent to the development of the disease, but they may be the first presenting signs and in some cases they may precede the primary disease manifestation by many years.Aims:The aim of our study was to study the spectrum of dermatoses in diabetics, to know the frequency of dermatoses specific to diabetes mellitus (DM), and to establish the mucocutaneous markers of DM.Material and Methods:The study was conducted at a diabetic clinic and our department between September 2008 and June 2010. Two hundred and twenty-four diabetic patients were included in the study group and those with gestational diabetes were excluded. Healthy age- and sex-matched individuals were taken as controls.Results:The male to female ratio was 1 : 1.21. Type 2 DM was seen in 89.7% and type 1 DM in 10.3% of the patients. Dermatoses were seen in 88.3% of the diabetics compared to 36% in non-diabetic controls (P<0.05). Cutaneous infections were the most common dermatoses followed by acanthosis nigricans and xerosis in diabetics. Type 2 DM was found to have an increased risk of complications than type 1 DM. Complications of diabetes were seen in 43.7% of the diabetic cases. Diabetic dermopathy, loss of hair over the legs, diabetic foot ulcer, and so on, were found to be the cutaneous markers of DM in our group of cases.Conclusion:Dermatoses were more common in diabetics than non-diabetics. Cutaneous infections formed the largest group of dermatoses in DM.

Prevalence of skin changes in diabetes mellitus and its correlation with internal diseases: A single center observational study

“…Various study reported age of presentation of Type 2 DM patients with skin manifestation is between 5 th to 6 th decade. [ 10 13 14 ] Age of presentation of Type 2 DM of our study populations is 51.21 ± 10.38 which matches with previous study findings. Among the patients presented with skin manifestations 15% was Type 1 and 85% Type 2 DM.…”

Relation between cutaneous and extracutaneous complications in pediatric patients with type 1 diabetes

“…where they reported prevalence of 15.1% and 15.2% respectively. 9 , 21 Several cutaneous mediators have been suggested to cause pruritus and seemed to be linked to metabolic changes observed in diabetes. Diffuse persistent pruritus without an identifiable clinical cause (pruritus sine material) as well as forms of prurigo, especially prurigo simplex subacuta are commonly observed in patients with diabetes.…”

Association of systemic diseases with cutaneous dermatosis in elderly population: Preliminary observation at a rural tertiary care centre

“…[ 6 7 8 9 ] There are studies showing association of dermatosis with specific systemic diseases like diabetes or cardiovascular conditions in general population, but not specifically in the geriatric age group. [ 10 11 12 13 14 15 16 ] This study focuses only on the geriatric age group, studies on them showing the association of dermatosis with systemic diseases is lacking.…”