A clinicopathological study of mediastinal masses operated in a tertiary care hospital in Eastern India in 3 years with special reference to thymoma

Dasgupta, Senjuti; Bose, Debdas; Bhattacharyya, Nirmal Kumar; Saha, Manika; Biswas, Keya; Biswas, Pranab Kumar

doi:10.4103/0377-4929.174818

Cited by 11 publications

(20 citation statements)

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“…1,7,8,11 In the mediastinum the majority of the lesions were seen in the anterior mediastinum similar to other studies. 16,17 In the present study haematolymphoid malignancy was the most type of malignancy in the mediastinal region. We did not have a single case of thymoma which was the most common mediastinal lesion in the other studies.…”

Section: Non Neoplastic Lesionssupporting

confidence: 49%

Computed Tomography Guided Fine Needle Aspiration Cytology of Lung and Mediastinal Lesions

Gadodiya¹,

Patil²,

Kumbhalkar³

et al. 2019

IJCMR

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Introduction: Computed tomography guided fine needle aspiration cytology is a safe and well established technique for the diagnosis of lung and mediastinal lesions. This study was carried out in the department of pathology in the tertiary health care and teaching institute where radiology department is well established. The aim was to study the cytomorphology of the spectrum of the lung and mediastinal lesions and to correlate the cytological diagnosis with the radiological diagnosis. Material and methods: Computed tomography guided fine needle aspiration cytology was done in 90 pateints after taking written consent of the patient. Patients were explained the benefits and risks of the procedure. The results were analysed. Results: A total of 90 patients were included in the study. There were 81 patients of lung lesions and nine patients of mediastinal lesions. There were 63(70%) males and 27(30%) females. Adequate aspirate was obtained in 77 patients giving the adequacy rate of 85.55%. Adenocarcinoma was the most common type of lung malignancy and Non Hodgkins Lymphoma was the most common malignancy in the mediastinum. Inflammatory lesions were seen in 13 cases. Granulomatous lesions were found in six patients. One interesting case of hydatid with aspergillosis was diagnosed on cytology smears, which on radiology was diagnosed as neoplastic. Pneumothorax was seen in three patients. No patient required chest tube insertion. Conclusion: Computed tomography guided fine needle aspiration cytology is a safe and reliable method for the diagnosis of lung and mediastinal lesions. It can help in early diagnosis and initiation of the treatment avoiding major surgical procedures.

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Section: Non Neoplastic Lesionssupporting

confidence: 49%

Computed Tomography Guided Fine Needle Aspiration Cytology of Lung and Mediastinal Lesions

Gadodiya¹,

Patil²,

Kumbhalkar³

et al. 2019

IJCMR

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“…The peak age of these lesions were in the 4 th and 5 th decades and they had an approximate M: F ratio of 1: 1. This was in concordance with the studies conducted independently by Dasgupta et al and Shrivastava et al 4,5 In this study 66% (103) of the lesions were found in the anterior mediastinum, 12% (33) in the middle mediastinum, 8% (13) in the posterior mediastinum and 5% (8) in the superior mediastinum. A similar study by Sharma et al showed 36.7% involvement of the anterior compartment followed by middle (33%) and posterior (30%).…”

Section: Discussionsupporting

confidence: 93%

Histopathological Profile of Mediastinal Lesions- A Five-Year Study From a Tertiary Care Centre in South India

Amanullah¹,

Vilasiniamma²,

Pothen³

et al. 2017

jemds

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BACKGROUNDThe mediastinum is the central limited space of the thoracic cavity, which houses a variety of neoplastic and non-neoplastic lesions. Accurate diagnosis is warranted owing to the variable therapeutic and prognostic implications. The aims of this study are to study the frequency and distribution of mediastinal tumours and tumour-like lesions and to study the histomorphological patterns of the various mediastinal lesions.

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“…Age distribution of all these cases was between 04 -70 yrs. [1][2][3][4][5][6][7][8][9][10][11][12] Out of total 43 cases we encountered 39 cases (90.60 %) were in adult age group (>16 yrs.) and the mean age in adults was (47.7 yrs.).…”

Section: Resultsmentioning

confidence: 99%

Histopathological Spectrum of Mediastinal Lesions in a Tertiary Care Centre, Andhra Pradesh, India

Parasa¹,

Remala²,

Turlapati³

2019

jemds

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BACKGROUNDMediastinal lesions are uncommon and infrequent, encountered as mediastinal masses with wide histopathological spectrum which cause diagnostic difficulty to the clinicians and radiologists because of the variations of presenting symptoms, locati on and accessibility. Mediastinal lesions also pose difficulty in obtaining samples directly by Fine Needle Aspiration or Needle Core Biopsy technique, Ultra Sound/ Computed Tomography guided techniques aid in getting adequate material and to arrive at a definitive diagnosis in cases where resection of the lesion is not possible, and accessibility is poor. We wanted to present the spectrum of histopathological diagnosis of various mediastinal lesions both benign and malignant, encountered in this institution, a tertiary care center in India. METHODSThis is a retrospective study conducted from June 2015-December 2018 on Fine Needle Aspirations (FNA), Needle Core Biopsies (FNB) and surgically resected specimens of all mediastinal lesions sent to the Department of Pathology for histopathological examination. RESULTSA total of 43 cases of mediastinal lesions was taken into consideration. Out of these 43 cases, 17 (39.53%) were CT guided FNA, 5 (11.63%) CT guided FNBs and 21 (48.84%) were excised specimens. In 3 (6.97%) of these cases of FNA diagnosis was inconclusive and in 2 (4.65%) cases no opinion could be given as material was necrotic and inadequate. Of the total 43 cases 27 (62.8 %) cases were males and about 16 (37.2%) were female patients. M:F ratio was 1.7:1. Age distribution was between 04 -70 yrs. 4 (9.30%) of the cases were in paediatric age group (<16 yrs.) and 39 (90.60 %) were in adult age group (>1 6 yrs.). Mean age in adults was (47.7 yrs.). CONCLUSIONSThe present study emphasizes on the importance of awareness of various lesions that can occur in mediastinum, spectrum of histopathological variants and a definitive diagnosis in guiding the treating clinician to initiate the appropriate treatment at the earliest especially in cases of malignancies and non resectable lesions. Wherever necessary IHC should be done. In the present study, thymic lesions and lymphomas are the most common lesions encountered in adults (8 and 7 of the total 43 lesions). In paediatric age group, we encountered two thymic cysts and two lymphomas of which one was Hodgkin's and the other was Non-Hodgkin's lymphoma. HOW TO CITE THIS ARTICLE: Parasa GD, Remala KR, Turlapati SPV. Histopathological spectrum of mediastinal lesions in a tertiary care centre, Andhra Pradesh, India. BACKGROUND Mediastinal lesions are uncommon lesions which occur in the central portion of the thoracic cavity, limited by pleural cavities laterally, thoracic inlet superiorly, the diaphragm inferiorly and vertebral column posteriorly. Diagnosis of these lesions is a difficult task for clinicians, radiologists and pathologists because of its variable presentation clinically, inaccessibility and also due to histomorphological variations. Mediastinal masses present as space occupying masses situated in differ...

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A clinicopathological study of mediastinal masses operated in a tertiary care hospital in Eastern India in 3 years with special reference to thymoma

Abstract: This study reflects the incidence of different mediastinal masses in West Bengal with their clinicopathologic correlation.

Cited by 11 publications

References 0 publications

Computed Tomography Guided Fine Needle Aspiration Cytology of Lung and Mediastinal Lesions

Computed Tomography Guided Fine Needle Aspiration Cytology of Lung and Mediastinal Lesions

Histopathological Profile of Mediastinal Lesions- A Five-Year Study From a Tertiary Care Centre in South India

Histopathological Spectrum of Mediastinal Lesions in a Tertiary Care Centre, Andhra Pradesh, India

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