In this work, a novel circuit topology for a Low-Voltage Differential Signaling (LVDS) output driver with reduced power consumption is proposed. Also, a low-signal current version of the LVDS driver working with lower supply voltage is proposed along with a compatible differential current-mode receiver. Both the drivers and the receiver feature active-terminated ports that eliminate the need for a dedicated passive terminator for matching. An asymmetric impedance network on the output side of the driver selectively eliminates any reflections coming from the channel while providing a high output impedance to the outgoing signal. For a target signal swing at the receiver input, the proposed termination scheme helps to reduce the driver signal current to up to a third of the current required by a conventional LVDS driver using a passive termination at the output. The asymmetric impedance network consists of a scaled-down replica driver that drives a common drain stage acting as the load for the main driver. The proposed driver topology meeting all LVDS specifications has been implemented in 3.3-V thick-gate CMOS technology. Simulation results show an achievable data rate of 5 Gb/s while transmitting over a 7.5-in FR4 PCB backplane trace for a target BER of 10 −15 , with power consumption equal to 17.8 mW, which is 25% less than a conventional LVDS driver with passive source end termination proCircuits Syst Signal Process (2012) 31:31-49 ducing the same voltage swing at the receiver input. The low-current version of the driver has been implemented in 0.18-µm 1.8-V digital CMOS technology and shows similar performance over the same channel with a power consumption of 4.5 mW.