A combined procedure of supercritical fluid extraction and molecular distillation for the purification of alkylglycerols from shark liver oil

Antioxidant and Cytotoxic Activities of Distillates Purified by Means of Molecular Distillation from Ginger Extract Obtained with Supercritical CO2 Fluid

“…Considering various factors, multistage MD has more advantages than other purification technologies and has been widely applied to concentrate bioactive compounds that can be successfully concentrated in different distillates by regulating the operating parameters of multistage MD. To the best of our knowledge, there are some relevant reports on the combination of supercritical fluid extraction and multistage MD, such as purification of alkylglycerols from shark liver oil and obtaining the camellia oil with lower acid, whereas there is a lack of research devoted to the ginger extract purified by the combination of supercritical CO 2 fluid extraction and multistage MD …”

“…To the best of our knowledge, there are some relevant reports on the combination of supercritical fluid extraction and multistage MD, such as purification of alkylglycerols from shark liver oil and obtaining the camellia oil with lower acid, whereas there is a lack of research devoted to the ginger extract purified by the combination of supercritical CO 2 fluid extraction and multistage MD. [19,20] Antioxidants are used extensively for protecting the human body from oxidative damage and preventing several metabolic diseases and age-related degenerative disorders such as cancer, coronary atherosclerosis and Parkinson's disease. [21] Nowadays, some synthetic antioxidants have been added as preservatives to prepackaged food.…”

Enzymatic Synthesis of Ether Lipids Rich in Docosahexaenoic Acid with Squalene as Reaction Medium

“…Diacylglycerol ethers (DAGE) or 1‐ O ‐alkyl‐2,3‐diacyl‐sn‐glycerols are the major constituents available in the liver oils of various species of shark and dogfish (Bakes and Nichols, ; Bordier et al, ; Deprez et al, ). Monoacylglycerol ethers (MAGE) and AKG could be obtained via ethanolysis of DAGE catalyzed by lipase or sodium ethoxide followed by purification through supercritical fluid extraction and molecular distillation (Fernández et al, ; Tenllado et al, ; Vázquez et al, ). Multiple beneficial health effects of AKG have been revealed including stimulation of hematopoiesis and immunological defenses, sperm quality improvement, or antitumor and antimetastasis activities (Deniau et al, ).…”

Supercritical Extraction of Cobia (Rachycentron canadum) Liver Oil as a New Source of Squalene

“…Some studies have shown the fractions purification of substances such as ethyl esters, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) [11], acid esters of fish oils [12], and contaminants [13]. In recent studies, supercritical extraction has been applied for new fish species or by-products [14] or as an extraction method combined with other processes such as molecular distillation [15] in order to optimise the fractionation of compounds with biological activity such as alkylglycerols and squalene.…”