Coronavirus disease 2019 (COVID-19) continues to spread worldwide since its emergence in December 2019 in Wuhan, China, and as of January 3, 2021 more than 84.4 million cases and 1.8 million deaths have been reported. To predict COVID-19 cases in Algeria, we applied two models-the logistic growth model and the polynomial regression model-using the data on COVID-19 cases reported by the Algerian Ministry of Health from February 25 to December 2, 2020. Results showed that the polynomial regression model better fitted the data of COVID-19 in Algeria compared with the logistic model. The first model estimated the number of cases on January 19, 2021 to reach 387,673. This model can help Algerian authorities in the fight against this disease.