A comparative evaluation of bovine-derived xenograft (Bio-Oss Collagen) and type I collagen membrane (Bio-Gide) with bovine-derived xenograft (Bio-Oss Collagen) and fibrin fibronectin sealing system (TISSEEL) in the treatment of intrabony defects: A clinico-radiographic study

Abstract

Background and Objectives:The purpose of this study was to compare the efficacy of bovine-derived xenograft (Bio-Oss Collagen) and Type I collagen membrane (Bio-Gide) with bovine-derived xenograft (Bio-Oss Collagen) and fibrin fibronectin sealing system (TISSEEL) in the treatment of periodontal infrabony defects.Materials and Methods:Fourteen healthy patients in the age range of 20 to 60 years, showing bilateral or contralateral infrabony defects were selected. The defects were assigned randomly to Site A (bovine-derived xenograft [Bio-Oss Collagen] with bioresorbable Type I collagen membrane [Bio-Gide]) and Site B (fibrin fibronectin sealing system [TISSEEL] with bovine-derived xenograft [Bio-Oss Collagen]). The radiographic parameters were recorded at baseline, 6 months, and 9 months postoperatively.Results:All fourteen patients returned for recall at regular intervals till the completion of the study. Both the experimental groups showed clinically and radiographically statistically significant reduction in probing pocket depth and gain in clinical attachment level.Conclusion:Both groups showed potential for enhancing the periodontal regeneration with no statistically significant between the two groups; however, on comparison the Bio-Oss Collagen and TISSEEL group were slightly better.

Osteopromotion Capacity of Bovine Cortical Membranes in Critical Defects of Rat Calvaria: Histological and Immunohistochemical Analysis

“…A porous surface is in contact with the bone. A dense surface remains in contact with soft tissues to prevent the growth of fibrous tissue into the bone defect [28]. In the BG group, bone neoformation was observed in the form of islands and the connective tissue was less cellular, suggesting partial bone resorption and penetration of bone tissue.…”

A Comparative Evaluation of the Mechanical Properties of Two Calcium Phosphate/Collagen Composite Materials and Their Osteogenic Effects on Adipose‐Derived Stem Cells

“…Excellent mechanical property not only provides a mechanical support for bone formation, but also makes the materials conducive for use in clinical applications. Both HAPS and HTPS have Young's moduli similar to that of Bio-Oss Collagen, which has been widely used in clinical practice [ 58 , 59 ]. Although we were unable to attain a Young modulus equivalent to that of the natural bone, the mechanical strength achieved by using these biomaterials is stronger than that obtained by using collagen alone [ 60 ] and is enough for dental applications in which the tensile stress is relatively lower [ 46 ].…”

A collagen membrane influences bone turnover marker in vivo after bone augmentation with xenogenic bone

“…The porcine-derived type I and III collagen membrane has a bilayer structure, consisting of a compact outer layer and a porous inner layer of collagen ber bundles [10]. Both materials, alone and in combination by means of GBR-procedures, are frequently used in preclinical as well as clinical regenerative maxillofacial surgery [3,18,[31][32][33].…”