A comparative evaluation of the anticaries efficacy of herbal extracts (Tulsi and Black myrobalans) and sodium fluoride as mouthrinses in children: A randomized controlled trial

Megalaa, N; Thirumurugan, K; Kayalvizhi, Gurusamy; Sajeev, R; Kayalvizhi, EB; Ramesh, VV; Vargeese, Abhishek

doi:10.4103/ijdr.ijdr_790_16

Cited by 16 publications

(6 citation statements)

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“…While, the significant raise in S. mutans counts after 2 hours of mouth rinsing between the all-tested groups with significant difference among CHX and other mouth rinses in our study, may be due to the rapid drop of salivary pH or to the short duration of action of the utilized mouth rinses (22) .…”

Section: Means In the Same Column (Between Periods) With Different Ca...mentioning

confidence: 46%

The Antibacterial Effect of Pomegranate Peel and Guava Leave Extract Mouthwash on Oral Streptococcus Mutans in Scholar Students: A Controlled Clinical Study

Elkarkhy

Mahmoud

Alla³

et al. 2022

Al-Azhar Journal of Dental Science

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Objective: Pomegranate peel extract (PPE) and guava leave extract (GLE) were used for centuries and their therapeutic abilities were reported. Hence, this study was conducted to evaluate and compare the antimicrobial effect of mouthwashes prepared from pomegranate peel and guava leave extract on oral Streptococcus mutans (S. mutans) count in healthy subjects. Subject and methods: A total of one hundred healthy children aged between 6-12 years were enrolled in this study and equally divided into five equal groups (n=20) according to mouth rinse type used in this study. Group 1 used 2% chlorhexidine (CHX) mouthwash; group 2 used 10 % PPE mouthwash; group 3 used 15 % PPE mouthwash; group 4 used 10 % GLE mouthwash; while group 5 was use15 % GLE mouthwash. Samples of Saliva were collected after mouth rinsing at two-time intervals; immediately after mouth rinsing and 2 hours after rinsing. Mitis Salivarius agar medium was used to determine S. mutans count. Results: The results revealed that S. mutans count recorded a marked significant reduction in all studied groups immediately after mouth rinsing, then S. mutans count was increased significantly in all groups after 2 hrs. The lowest S. mutans count was recorded with the CHX group followed by15 % and 10% PPE groups respectively. While the lowest performance was observed in GLE 15% and 10 % groups respectively. Conclusions: The use of PPE mouthwash has a higher antimicrobial effect when compared to GLE in both concentrations.

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Section: Means In the Same Column (Between Periods) With Different Ca...mentioning

confidence: 46%

The Antibacterial Effect of Pomegranate Peel and Guava Leave Extract Mouthwash on Oral Streptococcus Mutans in Scholar Students: A Controlled Clinical Study

Elkarkhy

Mahmoud

Alla³

et al. 2022

Al-Azhar Journal of Dental Science

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“…18 Various studies have shown sodium fluoride mouth rinse (0.2%) to be effective in reducing S. mutans counts. [19][20][21][22] *p < 0.01, statistically highly significant; SD, standard deviation; 1-chlorhexidine mouthwash (0.2%); 2-sodium fluoride mouthwash (0.2%), 3-ethanolic licorice root extract; 4-aqueous licorice root extract **Results for Tukey post hoc test for group wise comparison p < 0.05 for group wise comparison between chlorhexidine mouthwash and sodium fluoride mouth wash and between chlorhexidine mouthwash and aqueous licorice root extract p < 0.05 for group wise comparison between ethanolic licorice root extract and sodium fluoride mouthwash (0.2%) and between ethanolic licorice root extract and aqueous licorice root extract A limited comparison of the present study to other studies can be done as from the available literature it has been found that only few in vitro studies have assessed the effects of licorice root on S. mutans.…”

Section: Discussionmentioning

confidence: 99%

In Vitro Analysis of Licorice (Glycyrrhiza glabra) Root Extract Activity on Streptococcus mutans in Comparison to Chlorhexidine and Fluoride Mouthwash

Malvania¹,

Sharma²,

Sheth³

et al. 2019

The Journal of Contemporary Dental Practice

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Aim: The present study was done to determine the activity of licorice root extract on Streptococcus mutans (S. mutans) in comparison to chlorhexidine and fluoride mouthwash. Materials and methods: In the current study, the different concentrations of aqueous and ethanolic licorice root extract were subjected to microbiological assay and zone of inhibition was determined against S. mutans by agar ditch method. Minimum inhibitory concentration (MIC) of aqueous and ethanolic solution was obtained by using broth dilution method and agar dilution method. Chlorhexidine and fluoride mouthwash were kept as a positive control in the present study. One-way ANOVA along with Tukey post hoc test were used at 5% level of significance to analyze data. Results: Mean zone of inhibition of chlorhexidine mouthwash, fluoride mouthwash, aqueous and ethanolic licorice root extracts against S. mutans at 24 hours were 23 mm, 14.2 mm, 15.8 mm and 22.4 mm, respectively. Minimum inhibitory concentration of aqueous and ethanolic licorice root extract on S. mutans was 20 mg/mL and 12.5 mg/mL, respectively by both broth dilution method and agar dilution method. Conclusion:The antibacterial effect produced by ethanolic licorice root extract on S. mutans was comparable to chlorhexidine mouthwash while significantly higher in comparison with aqueous form and fluoride mouthwash. Clinical significance: The interest in the plants with antibacterial and anti-inflammatory activity has increased now days to treat various dental diseases as consequences of current problems associated with the conventional agents. Licorice root is easily available, economically feasible and culturally acceptable and may possess minimal side effects as compared to conventional means of chemicotherapeutic agents used for reduction of S. mutans in oral cavity and hence can be recommended for prevention of dental caries.

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“…The final solution was formulated by dissolving 0.4 g of extract in 10 ml of deionized water. The same method was done with clove buds samples except that these buds were already dried (17) .…”

Section: Preparing Of Herbal Extracted Disinfectant Solutionsmentioning

confidence: 99%

Effect of Some Disinfectant Solutions on the Adherence of Candida albicans to Three Types of Acrylic Resin Denture Base Materials

Ahmed¹,

Jaffer²

2020

SDJ

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Objective: Microbial adhesion to denture surface is problematic for denture wearers, especially those with impaired dexterities. This study aimed to evaluate the effectiveness of two plant extracts (clove and Basil) in addition to Chlorhexidine on candida Albicans adherence to (heat, cold, light) activated acrylic denture base materials. Methods: Two herbal extracted clove (Eugenia caryohyllata) and Basil (Ocimum basilicum) were prepared by drying, ground to powder, and extracted with ethanol chlorhexidine gluconate of 0.12% were used as three disinfectant solutions. One hundred and five square acrylic samples were prepared from (heat, cold, and light) activated acrylic resin denture base materials in dimensions of 10×10×2 mm for the study. The disk diffusion test was used to determine the susceptibility of C. Albicans to disinfectant solutions. The adhesion of yeast to the acrylic resin samples was measured with a light microscope by measuring the number of fungal cells in the corners of the square and expressed as no. of cells/mm2. Statistical analysis was done by ANOVA to compare the mean of readings between disinfectant solutions and post-hoc t-test in which the p-value is less than 0.05. Results: Statistically significant differences (p<0.05) of adhesion of C.albicans were found on the surfaces of three types of activated acrylic resin materials with means of 19.18, 46.25, and 26.50 cell/mm2on heat, light, and cold cure respectively and after immersing the specimens on the disinfectant solutions regarding the highest effect of the disinfectant solutions was seen in chlorhexidine gluconate of 0.12% which demonstrate 3.11, 5.89 and 5.43 cell/mm2 followed by Basil with means of 6.75, 13.57 and 10.11 cell/mm2 on heat, light and cold cure acrylic resin specimens correspondingly, then the clove and finally distilled water. Conclusions: Both clove buds and basil leaves extracted solutions exhibited high antifungal activity besides Chlorhexidine on the surface of denture base materials. The highest inhibition zone was seen in Chlorhexidine, followed by Basil, clove, and distilled water, respectively. The number of fungal cell adhesion to the three types of denture base was decreased in the three disinfectant solutions when compared to distilled water (control group).

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A comparative evaluation of the anticaries efficacy of herbal extracts (Tulsi and Black myrobalans) and sodium fluoride as mouthrinses in children: A randomized controlled trial

Cited by 16 publications

References 0 publications

The Antibacterial Effect of Pomegranate Peel and Guava Leave Extract Mouthwash on Oral Streptococcus Mutans in Scholar Students: A Controlled Clinical Study

The Antibacterial Effect of Pomegranate Peel and Guava Leave Extract Mouthwash on Oral Streptococcus Mutans in Scholar Students: A Controlled Clinical Study

In Vitro Analysis of Licorice (Glycyrrhiza glabra) Root Extract Activity on Streptococcus mutans in Comparison to Chlorhexidine and Fluoride Mouthwash

Effect of Some Disinfectant Solutions on the Adherence of Candida albicans to Three Types of Acrylic Resin Denture Base Materials

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