A Comparative Pharmacognostical Evaluation of Three Botanical Source Plants of Jivanti

Naik, Raghavendra; Harisha, C R; Acharya, Rabinarayan

doi:10.22159/ijpps.2018v10i2.22915

Cited by 9 publications

(10 citation statements)

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“…Since the plant A. excelsa is useful in the traditional medicine for the treatment of some ailment, it is important to standardize it for use as a drug. The pharmacognostic constants such as diagnostic microscopic features, powder characteristics, and the physicochemical evaluation with numerical standards reported in this work could be useful for the compilation of a suitable monograph for its proper identification [24,25].…”

Section: Estimation Of Total Phenolmentioning

confidence: 96%

Pharmacognostic and Phytochemical Investigation of Ailanthus Excelsa Roxb. Bark

Bhalke

Giri

2020

Asian J Pharm Clin Res

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Objective: The present investigation aims at detail pharmacognostic study of the bark of Ailanthus excelsa Roxb. (BAE). A. excelsa is an important plant in Indian system of medicine belonging to the family Simaroubaceae. Methods: BAE was studied for various pharmacognostic evaluation parameters such as examination of morphological and microscopic characters and physicochemical evaluation. The total phenolic content was determined using Folin–Ciocalteu reagent spectrophotometrically and calculated as gallic acid equivalent (GAE/g). Results: The morphological studies revealed that BAE is yellowish-brown in color with a smooth texture and characteristic odor. Microscopical studies indicated the presence of cork, cortex with a group of stone cells in BAE with secondary phloem region. Prismatic and acicular raphides calcium oxalate crystals were observed. The total ash value of BAE was found to be 8.95%. Bark powder was successively extracted in Soxhlet extractor using solvents from low polarity to high polarity such as petroleum ether, chloroform, ethyl acetate, and methanol. Alkaloids, glycosides, tannins, triterpenoids, carbohydrates, and flavonoids are present when the preliminary phytochemical investigation was done. The total phenolic content in BAE was found to be 9.95 mg GAE/g. Conclusion: The results obtained from the study provide information for proper identification and standardization of plant.

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Section: Estimation Of Total Phenolmentioning

confidence: 96%

Pharmacognostic and Phytochemical Investigation of Ailanthus Excelsa Roxb. Bark

Bhalke

Giri

2020

Asian J Pharm Clin Res

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“…Macroscopical study is the morphological description of the seed which can be seen by naked eyes and it was performed by following the standard methods to determine the taste, size, color and odor of the seeds of Nigella sativa [10].…”

Section: Macroscopical Evaluationmentioning

confidence: 99%

Pharmacognostical, Phytochemical and Pharmacological Evaluation for the Abortifacient Potential of the Seeds of Nigella Sativa L.

Thakur¹

2022

JASR

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Nigella sativa L (Ranunculaceae family) or commonly known as black cumin has long been used as a phytomedicine for antidiarrhea, appetite enhancer, diuretic, antibacterial, analgesic, anthelmintic, various skin diseases, anti-inflammatory, back pain, hemiplegia (paralysis of the hands or feet) and rheumatism. The objective of this study was to investigate pharmacognostical, phytochemical features, antioxidant activity and abortifacient effects of ethanol and aqueous extracts of Nigella sativa seed by using DPPH assay method and pregnancy maintenance model respectively. The different pharmacognostical parameters were evaluated as per standard protocols with some modifications. The preliminary phytochemical studies were performed with various reagents and chemicals on seed extracts in order to determine the various secondary metabolites. The ethanol and aqueous extracts of Nigella sativa seeds were screened for in-vitro antioxidant activity by oxygen radical scavenging such as 1, 1-diphenyl-2- picrylhydrazyl (DPPH) method. Abortifacient activity was studied in rats at 400 mg/kg doses administered orally from 8thto 20thdayof pregnancy. Rats were laparotomised on 21st day. Weight of fetus, percentage of abortion and thelive and dead fetuses were observed in both horns of the uterus. Pharmacognostical studies reveal the macroscopical characters of Nigella sativa seeds. Phytochemical screening of the ethanol and aqueous extracts of Nigella sativa seeds revealed the presence of secondary metabolites like alkaloids, carbohydrates, proteins and amino acids, tannins, saponins, glycosidesand flavonoids. The ethanol and aqueous extracts showed good dose dependent free radical scavenging property. IC50 values for aqueous and ethanol extracts were calculated by DPPH method. Aqueous extract have shown more free radical scavenging power as compared to ethanol extract. Ascorbic acid was used as standard. In this experiment, abortion is induced by using pregnancy maintenance model. In contrast, no live foetus was recorded in the animals treated with mifepristone as well as the 400 mg/kg, p.o. body weight of the ethanolic and aqueous extract having live foetus. Whereas ethanolic and aqueous extract having dead foetus and there was no dead foetus in the mifepristone treated animals. The ethanolic and aqueous extract of Nigella sativa at doses of 400 mg/kg has abortifacient effects, supporting its uses in traditional medicine. Further studies on the isolation of bioactive phytoconstituents of Nigella sativaseeds and their mechanism of action are strongly recommended before its application to humans.

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“…Macroscopical study is the morphological description of the leaf which can be seen by naked eyes and it was performed by following the standard methods to determine the shape, size, color, and odor of the leaves of G. dipterosperma Kurz. [10].…”

Section: Macroscopical Evaluationmentioning

confidence: 99%

“…Microscopical evaluations are the histological character of the organized drug and it was made on a qualitative basis [10].…”

Section: Microscopical Evaluationmentioning

confidence: 99%

Pharmacognostical, Preliminary Phytochemical Screening and in Vitro Antioxidant Activity of Hydromethanol Extract of Gordonia Dipterosperma Kurz.

Lapasam

Lalthasanga

Nongkhlaw

et al. 2020

Asian J Pharm Clin Res

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Objective: This research is to evaluate the pharmacognostic parameter, phytochemical analysis, and in vitro antioxidant properties of hydromethanol extract. Method: This study carries out the collection and authentication of the plant, extraction, pharmacognostic study, preliminary phytochemical screening, and antioxidant property of leaves hydromethanol extract were evaluated by scavenging the following free radicals – DPPH (2,2-diphenyl- 1-picrylhydrazyl), hydrogen peroxide, nitric oxide, and reducing power. One-way analysis of variance (ANOVA) followed by Dunnett’s test was performed. The minimum value of *p˂0.05 considered as significant, **p˂0.01 and ***p˂0.001. Results: Powder microscopy of the leaves showed the presence of stomata, calcium oxalate crystals, trichome, fibers, and oil glands. The total ash was considered to be 3.75%, water-soluble ash 1.25%, and acid-soluble ash 3%. Hydromethanol (3:7) extract yielded 38.8%, moisture content 15.6%. Preliminary phytochemical screening of the extract showed the presence of carbohydrates, glycoside, saponin, phenol, tannin, flavonoid, and steroid. The total flavonoid content was considered to be 32.25 mg/g of quercetin and the total phenolic content of the extract was found 610 mg/g of gallic acid. The IC50 radical scavenging effect of extract and gallic acid was considered to be 3.62 and 3.46 for 2,2-diphenyl-1-picrylhydrazyl, 10.4 and 24.73 for hydrogen peroxide, and 48.76 and 58.83 for nitric oxide. Conclusion: The phytochemical constituents of the extract were well-known pharmacologically active chemicals and significant antioxidant potential was shown by the extract. This study finds out the rationality of the use of this plant as a medicinal plant. Further studies would be needed to explore their potential as a treatment for fever, diarrhea, and dysentery.

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A Comparative Pharmacognostical Evaluation of Three Botanical Source Plants of Jivanti

Cited by 9 publications

References 1 publication

Pharmacognostic and Phytochemical Investigation of Ailanthus Excelsa Roxb. Bark

Pharmacognostic and Phytochemical Investigation of Ailanthus Excelsa Roxb. Bark

Pharmacognostical, Phytochemical and Pharmacological Evaluation for the Abortifacient Potential of the Seeds of Nigella Sativa L.

Pharmacognostical, Preliminary Phytochemical Screening and in Vitro Antioxidant Activity of Hydromethanol Extract of Gordonia Dipterosperma Kurz.

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