A comparative, randomized, controlled study on clinical efficacy and dental staining reduction of a mouthwash containing Chlorhexidine 0.20% and Anti Discoloration System (ADS)

Abstract

SummaryIntroduction. A good control of bacterial plaque is an essential factor for the success of periodontal therapy, therefore it is the main objective that the clinician together with the patient must get to have a healthy periodontium. The plaque control with mouthwashes is the most important home therapy as it helps to reduce the formation of plaque between the mechanical removal with a toothbrush. Aim. Authors analyzed the clinical data from a trial carried out with 3 different mouthwashes containing 0.2% Chlorhexidine (CHX). In addition, the ADS (Anti Discoloration System -Curaden Healthcare) was tested in comparison with the other mouthwashes without this system. Materials and methods. We tested antiplaque activity showed by 3 of the most commercialized mouthwashes, moreover, we tested the ability in reducing the dental staining related to the oral assumption of Chlorhexidine. Discussion and conclusion. Our results demonstrated the clinical efficacy of the 3 mouthwashes with CHX. Particularly performing was the anti discoloration system (Curaden Healthcare), with a clinical detection of dental stainings significantly less than the others tested. This study demonstrated the clinical efficacy of ADS system in the reduction of tooth staining, without a loss of antiplaque activity with respect to the competing mouthwashes containing CHX.

In Vitro Color Stability Evaluation of Three Polished and Unpolished Nanohybrid Resin Composites Immersed in a 0.12% Chlorhexidine-Based Mouthwash at Different Times

“…This is important to keep in mind as it has been reported that the size and distribution of filler can be related to color changes [ 3 , 5 ]. In addition, some reports have related external discoloration of the resin composite to large filler particles as they provide increased surface roughness [ 17 , 24 ].…”

“…However, adverse effects of CHX present in mouthwashes have been reported (dysgeusia and dental pigmentation being among the most common) depending on its dosage. This has led to the suggestion over the years of different CHX concentrations to balance beneficial and adverse effects in order to improve patient treatment [ 24 ]. The Food and Drug Administration (FDA) suggests the use of CHX as a mouthwash in 10 to 20 mL presentations with concentrations of 0.12% and 0.2% for approximately 30 s and for a period that can vary between 2 and 4 weeks [ 1 , 3 ].…”

Marginal Bone Loss Compared in Internal and External Implant Connections: Retrospective Clinical Study at 6-Years Follow-Up

“…Antibiotic therapy (amoxicillin and clavulanic acid 1 g or clarithromycin 1 g in case of allergy, twice daily for 7 days after surgery) and analgesic treatment (non-steroidal anti-inflammatory drugs, as required) were prescribed for each patient. Mouth rinses with a solution of chlorhexidine-digluconate (0.20%) twice daily for 10 days were recommended [ 40 , 41 , 42 ]. One week after the surgery, the sutures were removed.…”

Various applications of chlorhexidine as an antimicrobial agent in dentistry: A review

“…Cetyl pyridium chloride has been used, investigated and proved that it is as efficient as chlorhexidine is in combination with the alcohol along with, this new formulation reduces the unpleasant side effects of mucosal irritation. [3][4][5][6][7][8][9] The most common side effect by the use of the chlorhexidine mouthwash is brownish discoloration of the teeth, brownish discoloration of restoration if present in the oral cavity, and discoloration of the tongue. Staining which has been done by the use of chlorhexidine mouth wash, can not be easily removed with the help of tooth brushing.…”

“…Alternative to this, use of chlorhexidine chip, containing 2.5 mg of chlorhexidine which is present in cross linked matrix of gelatin is placed in to the periodontal pocket, results in inhibition of the bacteria up to 99 %. [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18] Chlorhexidine also helps in the treatment of oral malodor. The use of chlorhexidine after any periodontal surgery, results in enhancing the wound healing.…”