A Comparative Study of Collagen Dressings Versus Conventional Dressings in Wound Healing in Chronic Ulcer

Choudhary, Deepak; Insen, Swapnil Garg; Goyal, Sandeep; Chabbra, Umesh; Singal, Gopal

doi:10.14260/jemds/2017/82

Cited by 2 publications

(1 citation statement)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Choudhary et al in another prospective study on 60 patients with chronic ulcers compared the efficacy of collagen dressing with that of conventional dressing in the management of chronic ulcers and their healing process. 19 For 30 patients, collagen dressing was done and for rest conventional dressing. The granulation tissue appeared in around 2 weeks in maximum cases in collagen dressing group, i.e.…”

Section: Appearance Of Granulation Tissuementioning

confidence: 99%

A comparative study of collagen-based dressing versus conventional dressing in chronic ulcers

Chaurasia¹,

Diwaker²,

Garg³

2021

Int J Res Med Sci

View full text Add to dashboard Cite

Background: Collagen is a fibrous structure, proline-rich protein, comprised of three α-chains, plays an important role in each stage of wound healing, attracts fibroblasts and keratinocytes which in turn encourages debridement, angiogenesis and re-epithelializationMethods: This is a prospective cohort study. After obtaining ethical clearance from Institute’s ethical committee, all the patients fulfilling inclusion criteria were enrolled and written consent was obtained from all the patients. Detailed history was enquired and recorded on a predesigned proforma. The ulcer healing, analysed as- Time required for appearance of healthy granulation tissue, 50% reduction in ulcer size, complete healing time, requirement of skin grafting, time required in return to daily activities.Results: A significant decrease in time required for 50 % reduction in wound size with a mean difference of 18.5 in collagen group patients when compared to 37.5 and 33.0 in Normal saline group patients and Povidone iodine group patients. Chi square test was applied to assess the difference in proportions between groups t test was applied to compare the mean between the groups. P<0.05 was considered as statically significant.Conclusions: Healing with collagen particles is early, compared to the conventional dressings with lesser requirement of skin grafting, number of dressings, shorter hospital stay. Dressing changed every 3-4 days. Healing occurs by formation of early granulation tissue and wound contraction.

show abstract

Section: Appearance Of Granulation Tissuementioning

confidence: 99%

A comparative study of collagen-based dressing versus conventional dressing in chronic ulcers

Chaurasia¹,

Diwaker²,

Garg³

2021

Int J Res Med Sci

View full text Add to dashboard Cite

show abstract

Wound-Healing Peptides for Treatment of Chronic Diabetic Foot Ulcers and Other Infected Skin Injuries

et al. 2017

View full text Add to dashboard Cite

As the incidence of diabetes continues to increase in the western world, the prevalence of chronic wounds related to this condition continues to be a major focus of wound care research. Additionally, over 50% of chronic wounds exhibit signs and symptoms that are consistent with localized bacterial biofilms underlying severe infections that contribute to tissue destruction, delayed wound-healing and other serious complications. Most current biomedical approaches for advanced wound care aim at providing antimicrobial protection to the open wound together with a matrix scaffold (often collagen-based) to boost reestablishment of the skin tissue. Therefore, the present review is focused on the efforts that have been made over the past years to find peptides possessing wound-healing properties, towards the development of new and effective wound care treatments for diabetic foot ulcers and other skin and soft tissue infections.

show abstract

A Comparative Study of Collagen Dressings Versus Conventional Dressings in Wound Healing in Chronic Ulcer

Cited by 2 publications

References 5 publications

A comparative study of collagen-based dressing versus conventional dressing in chronic ulcers

A comparative study of collagen-based dressing versus conventional dressing in chronic ulcers

Wound-Healing Peptides for Treatment of Chronic Diabetic Foot Ulcers and Other Infected Skin Injuries

Contact Info

Product

Resources

About