Objective. The aim was to evaluate the flexural strength, flexural modulus, microhardness, Weibull modulus, and characteristic strength of six resin composite blocks (Grandio Blocs-GR, Tetric CAD-TE, Brilliant Crios-CR, Katana Avencia-AV, Cerasmart-CS, and Shofu Block HC-HC). Methods. Flexural strength and flexural modulus were measured using a three-point bending test and microhardness using the Vickers method. Weibull analysis was also performed. Results. The materials showed flexural strength ranging from 120.38 (HC) to 186.02 MPa (GR), flexural modulus from 8.26 (HC) to 16.95 GPa (GR), and microhardness from 70.85 (AV) to 140.43 (GR). Weibull modulus and characteristic strength ranged from 16.35 (CS) to 34.98 (TE) and from 123.45 MPa (HC) to 190.3 MPa (GR), respectively. Conclusions. GR, TE, and CR presented significantly higher flexural strength, modulus, Weibull modulus, and characteristic strength than the others.