A Comparative Study of Post Operative Analgesia Using Bupivacaine With Fentanyl and Bupivacaine With Buprenorphine in Gynaecological Surgeries Using Combined Spinal Epidural Technique

Abstract

This study was done to compare the efficacy of post-operative analgesia of epidural Fentanyl and buprenorphine along with bupivacaine in gynaecological surgeries. MATERIALS AND METHODS: 60 female patients posted for elective gynaecological surgeries were selected. They were randomly divided into 2 groups of 30 patients each. Group A received Fentanyl citrate 2mcg/kg with 10ml 0.125% Bupivacaine and Group B received Buprenorphine hydrochloride 3mcg/kg with 10ml 0.125% Bupivacaine epidurally post operatively. The parameters recorded were HR, RR, MAP, VAS, Wt of patient, OOA (onset of analgesia) and DOA (duration of analgesia). RESULTS: The significance was calculated using T test. The results showed that 0.125% bupivacaine and buprenorphine was better than 0.125% Bupivacaine with Fentanyl. CONCLUSION: Addition of buprenorphine to bupivacaine by epidural injection for post-operative analgesia improves the onset, the duration and the quality of analgesia, albeit keeping the possibility of late respiratory depression.