A comparative study of the effects of carbamazepine and the NMDA receptor antagonist remacemide on road tracking and car-following performance in actual traffic

Lack of effects between rupatadine 10 mg and placebo on actual driving performance of healthy volunteers

“…No straightforward explanation for this finding can be given. In previous studies with the same test the positive control condition did show effects (Ramaekers et al, 2002;Vuurman et al, 2004). Nonetheless there was also no impairment in the rupatadine treatment condition.…”

“…The car-following test (Ramaekers et al, 2002) involved the use of two vehicles driving behind each other on a secondary highway for approximately 25 min. The subject controlled the following vehicle, while the investigator controlled the leading car.…”

Effects of Medicinal Drugs on Fitness to Drive

“…The antiepileptic drugs carbamazepine and remacemide were compared in one driving study using healthy volunteers (Ramaekers et al 2002). The effects on driving performance were measured after 8, 10 and 12 days of a 12-day incremental dosing regimen.…”

The Benzodiazepine Stigma Persists

“…[3][4][5][6][7][8][9][10][11][12][13] Some of these medications have been associated with impairment in on-the-road driving tests and psychomotor tests in addition to being associated with motor vehicle accidents.…”