A comparative study on the fatty acid composition of the oils from five Bupleurum species collected from Turkey

Saraçoğlu, Hatice Taner; Zengin, Gökhan; Akın, Mehtap; Aktümsek, Apdurahman

doi:10.3906/biy-1112-51

Cited by 6 publications

(4 citation statements)

References 18 publications

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“…The present study’s findings coincide with the literature on the medical applications of different Bupleurum species [ 5 , 6 , 7 , 15 , 16 , 18 , 19 , 20 ]. The inactivities of the tested BLM, BLB, and HDEO toward all tested bacterial strains have been previously reported by several studies for some Bupleurum species [ 18 ], including B. lancifolium ; its essential oil [ 19 ] and crude extract [ 25 ] were devoid of activities against both Gram-negative and -positive bacteria. Intriguingly, the cytotoxic and anticholinergic activities of the BLM crude extract could be attributed to its contents of fatty acids and sterols (i.e., α-spinasteryl).…”

Section: Resultssupporting

confidence: 92%

“…The HDEO showed a stronger AChE inhibition potency compared to the two other fractions (IC 50 = 43.8 ± 2.7 µg/mL), which was three-to five-fold more effective than the BLB and BLM (Table 4). The present study's findings coincide with the literature on the medical applications of different Bupleurum species [5][6][7]15,16,[18][19][20]. The inactivities of the tested BLM, BLB, and HDEO toward all tested bacterial strains have been previously reported by several studies for some Bupleurum species [18], including B. lancifolium; its essential oil [19] and crude extract [25] were devoid of activities against both Gram-negative and -positive bacteria.…”

Section: Total Flavonoid (Tfc) and Phenol (Tpc) Contents And Antioxid...supporting

confidence: 91%

“…Hexacosane and pentacosane dominated the essential oil obtained from fruit oil, while the roots oil contained mainly hexadecanoic acid and heptacosane [ 18 ]. Another study reported the fatty acid composition of the oils extracted from B. lancifolium collected from the central Anatolia region of Turkey [ 19 ], reporting oleic acid, linoleic acid, and linolenic acids as the main components of the oils [ 19 ]. Moreover, hexane extract obtained from B. lancifolium leaves and seeds extract contained ω-3, ω-6, palmitic acid, and γ-linolenic acid and is considered an important source of ω-3 and ω-6 compounds among several Bupleurum species [ 20 ].…”

Section: Introductionmentioning

confidence: 99%

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Uncovering the Chemical Composition and Biological Potentials of Bupleurum lancifolium Hornem. from Jordan

Al-Bataineh,

Abu-Orabi,

Shannag

et al. 2024

Molecules

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The current study was designed to uncover the chemistry and bioactivity potentials of Bupleurum lancifolium growing wild in Jordan. In this context, the fresh aerial parts obtained from the plant material were subjected to hydrodistillation followed by GC/MS analysis. The main components of the HDEO were γ-patchoulene (23.79%), β-dihydro agarofuran (23.50%), α-guaiene (14.11%), and valencene (13.28%). Moreover, the crude thanolic extract was partitioned to afford two main major fractions, the aqueous methanol (BLM) and butanol (BLB). Phytochemical investigation of both fractions, using conventional chromatographic techniques followed by careful inspection of the spectral data for the isolated compounds (NMR, IR, and UV-Vis), resulted in the characterization of five known compounds, including α-spinasteryl (M1), ethyl arachidate (M2), ethyl myristate (M3), quercetin-3-O-β-d-glucopyranosyl-(1-4”)-α-L-rhamnopyranosyl (B1), and isorhamnetin-3-O-β-d-glucopyranosyl-(1-4”)-α-L-rhamnopyranosyl (B2). The TPC, TFC, and antioxidant activity testing of both fractions and HDEO revealed an interesting ABTS scavenging potential of the BLB fraction compared to the employed positive controls, which is in total agreement with its high TP and TF contents. Cytotoxic evaluation tests revealed that BLM had interesting cytotoxic effects on the normal breast cell line MDA-MB-231 (ATCC–HTB-26) and the normal dermal fibroblast (ATCC® PCS-201-012) and normal African green monkey kidney Vero (ATCC-CCL-81) cell lines. Despite both the BLB and BLM fractions showing interesting AChE inhibition activities (IC50 = 217.9 ± 5.3 µg/mL and 139.1 ± 5.6 µg/mL, respectively), the HDEO revealed an interestingly high AChE inhibition power (43.8 ± 2.7 µg/mL) that far exceeds the one observed for galanthamine (91.4 ± 5.2 µg/mL). The HDEO, BLM, and BLB exhbitied no interesting antimicrobial activity against Bacillus cereus, Bacillus subtilis, Staphylococcus aureus, Escherichia coli, or Pseudomonas aeruginosa.

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Section: Resultssupporting

confidence: 92%

Section: Total Flavonoid (Tfc) and Phenol (Tpc) Contents And Antioxid...supporting

confidence: 91%

Section: Introductionmentioning

confidence: 99%

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Uncovering the Chemical Composition and Biological Potentials of Bupleurum lancifolium Hornem. from Jordan

Al-Bataineh,

Abu-Orabi,

Shannag

et al. 2024

Molecules

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“…The family Fabaceae is the third-largest flowering plant family, consisting of about 482 genera and 1,200 species of evergreen trees, herbs, water plants, and shrubs [1]. A wide array of nutrients, such as proteins, amino acids, and fatty acids, are found in Fabaceae plants [2].…”

Section: Introductionmentioning

confidence: 99%

Cytotoxicity, Antioxidant Activities, GC-MS and HPLC Fingerprint Analyses of Different Extracts of Desmodium tortuosum (Sw.) DC

Elshazly,

Hamada,

Refahy

2023

Jordan j. pharm. sci.

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The family Fabaceae is the third-largest flowering plant family, and the genus Desmodium has exhibited a wide range of biological activities and a variety of chemical constituents. In the present study, different extracts of Desmodium tortuosum were evaluated for their cytotoxic and antioxidant activities, as well as their total phenolic content (TPC). The antioxidant activities were estimated using the 1,1'-diphenyl-2-picraylhydrazyl free radical (DPPH), while the cytotoxic activity was evaluated via the brine shrimp lethality test (BSLT). The antioxidant activity results revealed that the DPPH radical scavenging activity (SC50) ranged from 1.12 to 61.22 µg/ml with respect to ascorbic acid (SC50 = 7.45 µg/ml). Among all tested fractions, 90% methanol was the most active. On the other hand, the cytotoxic activities were arranged as follows: n-BuOH (LC50 = 310), EtOAc (LC50 = 350), and 70% methanol (LC50 = 380). High-Performance Liquid Chromatography-Fingerprint analyses were used to determine the chemical composition and relative proportions of phenolic compounds. GC-MS analysis indicated the presence of fatty acids and other compounds. The major identified compounds were Benzene (1-butyloctyl) (11.88%) and Himachalene <α-> (11.08%) for the ethyl acetate extract and 10-Undecenoic acid, methyl ester (25.50%) for unsaponifiable matter.

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Do Compositions of Lipid Fraction Correspond to Species Differentiation in Bupleurum L. (Apiaceae)?

Тыхеев

Anenkhonov

Жигжитжапова

et al. 2020

Plants

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Bupleurum L. has been widely used in various medical systems as an agent with a wide range of activities. The qualitative composition and content of lipid fraction components of the aerial parts of B. longifolium and B. chinense were elucidated in this work. The available data on the fatty acids (FAs) in Bupleurum plants were compiled and compared with species differentiation in the genus. As a result, the content of FAs in the studied Bupleurum plant species only partially corresponded to the species differentiation and, in some cases, contradicted it. The prognostic value of Bupleurum’s species differentiation for the identification of the potential composition of FAs was insignificant, and it was limited only by particular groups of species. This suggests that a complete phytochemical study of Bupleurum species needs to be conducted to determine the composition of FAs and to identify which species have a similar composition.

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A comparative study on the fatty acid composition of the oils from five Bupleurum species collected from Turkey

Cited by 6 publications

References 18 publications

Uncovering the Chemical Composition and Biological Potentials of Bupleurum lancifolium Hornem. from Jordan

Uncovering the Chemical Composition and Biological Potentials of Bupleurum lancifolium Hornem. from Jordan

Cytotoxicity, Antioxidant Activities, GC-MS and HPLC Fingerprint Analyses of Different Extracts of Desmodium tortuosum (Sw.) DC

Do Compositions of Lipid Fraction Correspond to Species Differentiation in Bupleurum L. (Apiaceae)?

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