A comparative study on the aphrodisiac activity of food plants &lt;i&gt;Mondia whitei, Chenopodium album,Ccucurbita pepo&lt;/i&gt; and &lt;i&gt;Sclerocarya birrea&lt;/i&gt; extracts in male wistar rats

Sewani-Rusike, CR; Iputo, JE; Ndebia, Eugene Jamot; Gondwe, Mavuto; Kamadyaapa, DR

doi:10.4314/ajtcam.v12i2.5

Cited by 8 publications

(7 citation statements)

References 16 publications

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“…At the 14 th day of study it was showed that mount and intromission latency was reduced more than the single dose and mount and intromission frequency and copulatory ef iciency was increased more than the single dose when compared with the control. At day 28 there was no much variation when compared to day 14 (Sewani-Rusike et al, 2015).…”

Section: Moringa Oleifera (Drumstick) (Moringaceae)mentioning

confidence: 81%

Aphrodisiac Activity of Nutraceuticals

Mruthunjaya

2020

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The name aphrodisiac is taken from Aphrodite who is penned as the Greek goddess of love, beauty and sex in an ancient folk tale. Dating from a remote period humans strive hard to improve their sexual powers but modern lifestyle and other environmental factors have resulted in many sexual dysfunctions . Current treatment strategies which had lead to unsuccessful results and high cost made man to search for alternative medicine or to include nutraceuticals in their food diet which improves aphrodisiac properties . There are hundreds of medicinal plants that can improve aphrodisiac activity and also there are herbs that have a nutraceutical value other than medicinal properties which improve aphrodisiac activity. There are many numbers of nutritional factors as well as phytochemical factors present in fruits and vegetables other than calories and fats which are helpful in providing nutritional health and to cure diseases. This review divulges about some nutraceutical food plants which are helpful for relieving sexual dysfunction or to improve sexual function.

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Section: Moringa Oleifera (Drumstick) (Moringaceae)mentioning

confidence: 81%

Aphrodisiac Activity of Nutraceuticals

Mruthunjaya

2020

ijrps

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“…Previous reports indicated that vitamin C supplementation significantly increased sperm count, sperm morphology, and sperm mobility in human semen [54, 55] and/or by mitigating physiological toxicity. C. album extract is reported to increase sperm count and sexual behavior and also its seed extract is reported as a potent sperm immobilizing agent [20, 56].…”

Section: Discussionmentioning

confidence: 99%

“…Mercury compounds have been reported to cause DNA breaks by means of free radical-mediated reactions that may lead to an increase in the occurrence of spermatozoa with anomalous heads [38]. Protection of DNA by vitamin C in sperms against endogenous oxidative damage was evident in previous reports [20]. C. album protects DNA damage in a manner similar to vitamin C. The antioxidant potential of C. album might benefit in protecting against Mercury-induced sperm DNA damage.…”

Section: Discussionmentioning

confidence: 99%

“…It has been screened for nutritional, phytochemical, antioxidant, and antibacterial activity [19]. C. album possesses aphrodisiac activity, cures male infertility, and increases the copulatory efficiency respectively [20]. Male rats and mice treated with ethanolic seed extract of the plant exhibited increased reproductive organs and body weight gain parallel with increased sperm count and sexual performance.…”

Section: Introductionmentioning

confidence: 99%

“…Male rats and mice treated with ethanolic seed extract of the plant exhibited increased reproductive organs and body weight gain parallel with increased sperm count and sexual performance. There was an improvement in sexual behavior and performance and an increase in sperm count in male mice and rats [20]. Nevertheless, C. album seed extract (CAE) also caused sperm death due to oxidative damage induced by the generation of ROS [21].…”

Section: Introductionmentioning

confidence: 99%

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Ameliorating potency of Chenopodium album Linn. and vitamin C against mercuric chloride-induced oxidative stress in testes of Sprague Dawley rats

Jahan

Azad

Ayub

et al. 2019

Environ Health Prev Med

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BackgroundMercury has been documented as an industrial risk that posed a serious danger to human health. Mercury exposure results in oxidative stress that may lead to the pathogenesis of male reproductive dysfunction. The present study investigated the ameliorating potential of Chenopodium album L. and vitamin C against mercuric chloride-induced oxidative deterioration of reproductive functions in adult male rats.MethodsGroup 1 (control) received saline. Group 2 received Mercury (0.15 mg/kg b.w, i.p) dissolved in distilled water. Groups 3 and 4 were given oral gavage of vitamin C (200 mg/kg b.w) and the ethanolic extract of C. album (200 mg/kg b.w) respectively, along with Mercury (0.15 mg/kg b.w, i.p). Group 5 was treated only with C. album (200 mg/kg b.w). After 30 days of the treatment, the rats were dissected and their testicular tissue and the cauda epididymis were used for biochemical analysis while blood plasma was used for protein determination.ResultsThe applied dose-treatment of Mercury-induced oxidative stress in the testis and cauda epididymis tissues of the rats was apparent by a noteworthy decrease in total protein, CAT, SOD, POD, and GST values while there was increase in ROS and TBARS levels. Furthermore, Mercury decreases daily sperm production and enhanced sperm DNA damage as noticeable by an increase in the head and tail length of comets and decrease in intact DNA. There was no significant effect on the body weight and the weight of the reproductive tissues. Treatment with C. album significantly ameliorated the total protein, ROS, and TBARS content. Similarly, the level of CAT, SOD, POD, and GST was significantly improved and the daily sperm production was significantly increased. Furthermore, C. album administration significantly protected Mercury-induced sperm DNA damage. The results of the extract treatment group were compared with those of vitamin C in detoxifying the oxidative stress and restoring the sperm parameters.ConclusionC. album showed protection against Mercury-induced oxidative stress by ameliorating antioxidant enzyme activity, daily sperm production, and DNA damage in rat testes. This suggests that C. album could be beneficial against toxicity induced by an environmental toxicant.

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