A Comparison of Conjoint Measurement with Self-Explicated Approaches

Sattler, Henrik; Hensel-Börner, Susanne

doi:10.1007/978-3-662-06395-8_5

Cited by 31 publications

(16 citation statements)

References 17 publications

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“…The online quantitative questionnaire involved a self-explicated conjoint methodology using successive ratings of three layers of the survey features: levels, attributes and domains 12 13…”

Section: Methodsmentioning

confidence: 99%

Comparing the needs and preferences of patients with moderate and severe dry eye symptoms across four countries

et al. 2019

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Background/aimsUnderstanding patients’ perspectives of their disease can inform drug development and treatment decisions. In this study, we compared the preferences and needs of patients with moderate and severe dry eye symptoms from four different countries.MethodsA quantitative questionnaire was developed based on the self-explicated conjoint methodology and was administered to 160 patients with moderate or severe dry eye disease (DED) from Australia, Germany, UK and the USA.ResultsPatients with moderate dry eye symptoms ranked ‘treatment satisfaction’ as the most important aspect, whereas ‘symptom bother’ was more relevant for those in the severe group. Both the moderate and severe groups classified treatment effectiveness as the most important treatment attribute. This result was consistent across the four countries, although US patients gave significantly higher scores than patients from other countries (p<0.001). Furthermore, patients from Australia ranked ‘treatment experience’ as significantly more important than the concern of side effects, whereas respondents from Germany exhibited the opposite trend (p<0.05 for both). The health burden of DED is reflected in the average European Quality of Life-5 Dimensions 5-level (EQ-5D) scores of 0.764 and 0.658 for patients with moderate and severe disease, respectively.ConclusionOur results confirm that across the countries in the study, moderate and severe DED has a major impact on patients’ quality of life and daily activities. By providing insight into the patient perspective of DED, our study helps identify outcomes that are important to patients and may guide future drug development and clinical decision-making.

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“…The online quantitative questionnaire involved a self-explicated conjoint methodology using successive ratings of three layers of the survey features: levels, attributes and domains 12 13…”

Section: Methodsmentioning

confidence: 99%

Comparing the needs and preferences of patients with moderate and severe dry eye symptoms across four countries

et al. 2019

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“…Here, we have discussed two examples, the self-explicated conjoint analysis (in DED) and the ACBC analysis (in NASH). The self-explicated methodology (11) was chosen because of its ability to handle a large number of attributes as identified in DED, while still providing low cognitive strain on the respondents. A previous methodological comparison confirmed that self-explicated approaches, due to the straightforward research design, data collection, and data analysis, require less time and investment than traditional methods of conjoint analysis 1 , which is advantageous in early development phases (11).…”

Section: Discussionmentioning

confidence: 99%

“…The self-explicated methodology (11) was chosen because of its ability to handle a large number of attributes as identified in DED, while still providing low cognitive strain on the respondents. A previous methodological comparison confirmed that self-explicated approaches, due to the straightforward research design, data collection, and data analysis, require less time and investment than traditional methods of conjoint analysis 1 , which is advantageous in early development phases (11). However, this study design is not suitable to identify benefit–risk trade-offs and therefore would be less suitable for regulatory decision making at the product submission stage.…”

Section: Discussionmentioning

confidence: 99%

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Patient Preference Studies During Early Drug Development: Aligning Stakeholders to Ensure Development Plans Meet Patient Needs

Cook

Cave

Holtorf³

2019

Front. Med.

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Although patient preferences have been studied broadly for marketed products or around the time of submission to authorities and launch, patient preference studies have rarely been used during the early drug development phases. In this paper, we formulate three hypotheses supporting the use of patient preference studies in early product development: (1) integration of the patient perspective into the development process from phase 1 onwards will result in healthcare solutions with outcomes that best address patients' needs; (2) a structured process to build patient-based evidence involving partnerships between patients and other key stakeholders will improve alignment of development activities with the needs of patients; (3) quantitative patient preference research built on robust qualitative insights is necessary to strengthen development decisions in the interests of patients. To illustrate such a structured process, we describe qualitative insights research (social media analysis and online bulletin boards) and quantitative patient preference studies in dry eye disease and non-alcoholic steatohepatitis conducted during early product development by a pharmaceutical company to generate patient-based evidence. The outputs from such early patient preference studies are being used to inform patient reported outcome strategies, clinical development strategies, product design and delivery features, and form the basis for early dialog with regulators, health technology assessment (HTA) bodies and payers to ensure focus and alignment on patient-relevant endpoints. Furthermore, to discuss and theoretically substantiate our hypotheses, we review how different groups and organizations are working to embrace fully the patient perspective in product development and healthcare decision-making. The hypotheses are commensurate with the general trend toward patient-centered healthcare and the activities initiated by regulators, HTA agencies, and patient organizations. We advocate that all healthcare players should actively contribute to aligning on best practices concerning choice of methodologies and engage in multi-stakeholder dialog along the entire product development chain, to realize health technologies that best meet the needs of patients.

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“…Comparisons of the accuracy of importance scores from self-explicated approaches vs. conjoint or choice-based techniques have produced mixed results. Sattler and Hesen-Börner (2000) reviewed 23 studies comparing conjoint and self-explicated approaches and found that only five (22 per cent) showed significantly better results in terms of reliability or predictive validity for conjoint measurement. They conclude that although conjoint measurement has theoretical advantages over self-explicated approaches, empirical analyses fail to confirm the superiority of conjoint measurement.…”

Section: Literature Reviewmentioning

confidence: 99%

Relative Value and Customer Choice in Loan Decisions: An Application of the Wallet Allocation Rule

Aksoy

Keiningham²,

Buoye

et al. 2016

Journal of Creating Value

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Purpose -This research applies the Wallet Allocation Rule (WAR) to provide marketing scholars and practitioners with a deeper understanding of the key drivers of loan selection and to estimate the relative value borrowers place on various attributes when selecting a loan provider among competitors.Design/methodology/approach -A survey of 642 credit union (CU) members from nine geographically dispersed USA CUs was conducted. WAR analysis was conducted to measure the relative value customers place on the selected variables within and across the financial institutions that were part of the borrowers' consideration sets.Findings -WAR analysis revealed stark differences in the value of factors in the selection of a bank or a credit union for first mortgages, suggesting that WAR analysis is a useful tool for understanding the relative value of various attributes in the selection of one loan provider over another.Originality/value -This research provides a significant contribution to both the service literature and the scientific literature in general by providing a Banking and ValueAksoy et al. 93user-friendly and scientifically tested analysis tool to measure relative value distances of ranked data and providing additional evidence for the usefulness of WAR analysis to better understand relative customer satisfaction and its implications for consumer behavior and service marketing.

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A Comparison of Conjoint Measurement with Self-Explicated Approaches

Cited by 31 publications

References 17 publications

Comparing the needs and preferences of patients with moderate and severe dry eye symptoms across four countries

Comparing the needs and preferences of patients with moderate and severe dry eye symptoms across four countries

Patient Preference Studies During Early Drug Development: Aligning Stakeholders to Ensure Development Plans Meet Patient Needs

Relative Value and Customer Choice in Loan Decisions: An Application of the Wallet Allocation Rule

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