“…These agents are approved for external application only and are not to be used as internal tissue adhesive because of the reactions, toxicity [8] and carcinogenicity. In the maxillofacial field, it has been used for wound closure on extraction sockets, face, sinus perforation in sinus lift [9] gingivectomy, mucogingival flaps, biopsy, superficial oral ulcerations, recurrent multiple Aphthous ulcers and leukemia, and other sites in general surgery like axilla, lungs [10], hearts [11], scalp wounds [4], circumcision [12] and perineum, trocar sites [13], as a heamostatic means to control bleeding from skin graft [14], hair transplant donor sites, cleft lip repair [7,15] face lifts, blepharoplasty [16], brow lifts and other cosmetic surgeries and to do various anastomoses of intestine, arteries [11] and nerves [17].…”