A Comparison of Dexmedetomidine with Propofol for Magnetic Resonance Imaging Sleep Studies in Children

Mahmoud, Mohamed; Gunter, Joel B.; Donnelly, Lane F.; Wang, Yu; Nick, Todd G.; Sadhasivam, Senthilkumar

doi:10.1213/ane.0b013e3181adc506

Cited by 179 publications

(104 citation statements)

References 49 publications

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“…Dexmedetomidine, which does not commonly result in respiratory depression, may be the optimal option for patients with pre-existing severe airway obstruction. Mahmoud et al (10) found that, compared with the use of propofol, dexmedetomidine showed improved preservation of the upper airway muscle tone and minimal airway collapsibility. Furthermore, ketamine has been shown to preserve the hypopharyngeal size in adults (11); however, this compound tends to increase respiratory secretions and induce laryngospasm.…”

Section: Discussionmentioning

confidence: 99%

Airway loss during inhalation induction of anesthesia with sevoflurane in a pediatric patient with laryngeal papillomatosis: A case report

Shen

2015

Experimental and Therapeutic Medicine

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Abstract. The aim of the present study was to report a failed inhalation induction of anesthesia with sevofluran in a pediatric patient with grade III laryngeal obstruction caused by laryngeal papillomatosis. Inhalation induction is recommended for the induction of anesthesia in pediatric patients. In the present case, due to the respiratory depression properties of the anesthetics, the partial airway obstruction developed into complete airway obstruction, followed by cardiac arrest. The patient survived after the surgeon managed to reconvert the complete airway obstruction into partial airway obstruction through the removal of part of the laryngeal papillomas. In conclusion, the reaction of the patient in the present case to sevoflurane inhalation induction suggests that this technique is not recommended for patients with pre-existing severe airway obstruction. In such cases, special consideration and preparation is required.

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Section: Discussionmentioning

confidence: 99%

Airway loss during inhalation induction of anesthesia with sevoflurane in a pediatric patient with laryngeal papillomatosis: A case report

Shen

2015

Experimental and Therapeutic Medicine

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“…Although, there is a limitation on use of propofol in remote anesthesia because it increases the risk of respiratory depression. Dexmedetomidine has been shown to have sedative properties without respiratory depression it seemed to us that dexmedetomidine had many characteristics of ideal sedative for remote anesthesia in pediatric radiotherapy [7].…”

Section: Discussionmentioning

confidence: 99%

Dexmedetomidine for Repeated Sedation in Pediatric Sedation During Consecutive Radiation Therapy

Kim

Baek

Byeon

et al. 2014

J Korean Dent Soc Anesthesiol

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External beam radiotherapy (EBRT) causes anxiety and claustrophobia in pediatric patients. To provide exact figures and radiation amounts, an appropriate sedation or anesthesia can be supplied. Alpha 2 agonist dexmedetomidine has been used for sedation and anesthesia in pediatric imaging. Dexmedetomidine has an advantage because it has minimal respiratory depression and no direct effects on myocardial function. We report repeated sedation with dexmedetomidine for 33 consecutive radiation therapies in 5 years old children. Dexmedetomidine is a selective α 2 -adrenoreceptor agonist that decreases sympathetic tone and attenuate the stress response to anesthesia and surgery. It was introduced during the 1990s as a sedative in the intensive care unit. Dexmedetomidine has no effect of myocardial function and minimal effect on respiratory function [4,5], these characteristics make an appealing agent for the ERBT in pediatric patients.We present a case about using of dexmedetomidine as the sole sedation anesthetics for 33 consecutive EBRT sessions in a 5 year old child. CASE REPORTA 5 year old female child (111 cm, 21.4 kg) was admitted to hospital with nausea, vomiting and headache that had lasted for 4 weeks. Magnetic resonance imaging (MRI) revealed a contrast enhanced 3.7 × 4.3 cm lesion in left parietal lobe. A glioblastoma was suspected and confirmed histologically after craniotomy with tumor resection. After surgery, 33 consecutive radiation therapies (involved field, two co-axial isocentric field, fractionated; cumulative dose 61.2 Gy) were implemented for duration of 7 weeks. In order to plan proper radiation

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“…Midazolam eklenmesi çocuk hastalarda derlenme ve taburculuk sürelerini uzatmaktadır. [12,13] Sonuç olarak, MRG işlemi esnasında günü birlik anestezi verilen hastalarda son yıllarda kullanılmaya başla-nan propofolün özellikle hemodinamik değişiklikler, MRG işlemine hazır hale gelme süreleri, derlenme …”

Section: Discussionunclassified

Comparison of comfort, recovery and discharge times of sodium thiopental and propofol anesthesia in pediatric patients who underwent outpatient anesthesia for magnetic resonance imaging

Adas¹,

Adas²,

Ergun³

et al. 2013

J Kartal TR

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A Comparison of Dexmedetomidine with Propofol for Magnetic Resonance Imaging Sleep Studies in Children

Cited by 179 publications

References 49 publications

Airway loss during inhalation induction of anesthesia with sevoflurane in a pediatric patient with laryngeal papillomatosis: A case report

Airway loss during inhalation induction of anesthesia with sevoflurane in a pediatric patient with laryngeal papillomatosis: A case report

Dexmedetomidine for Repeated Sedation in Pediatric Sedation During Consecutive Radiation Therapy

Comparison of comfort, recovery and discharge times of sodium thiopental and propofol anesthesia in pediatric patients who underwent outpatient anesthesia for magnetic resonance imaging

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