A comparison of EQ-5D time trade-off values obtained in Germany, The United Kingdom and Spain

Busschbach, Jan J. V.; Weijnen, Tom; Nieuwenhuizen, Martin; Oppe, S; Badia, Xavier; Dolan, Paul; Greiner, Wolfgang; Kind, Paul; Krabbe, Paul F M; Öhinmaa, Arto; Roset, Montserrat; Sintonen, Harri; Tsuchiya, Aki; Williams, Alan N.; Yfantopoulos, John; Charro, Frank de

doi:10.1007/978-94-017-0233-1_9

Cited by 29 publications

(32 citation statements)

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“…There appears to be a relatively large gap in the TTO scale around dead, the gap effect. This gap is in qualitative agreement with the results of Busschbach [8] The question is what do these gaps around dead signify? One may infer that the TTO fails to produce a continuous scale, whereas this is not the case for the VAS scale.…”

Section: Discussionsupporting

confidence: 88%

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The gap effect: discontinuities of preferences around dead

et al. 2005

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These results are interpreted in light of a descriptive QALY model. This model was expanded to include utilities worse than dead. The VAS task does not pick up that bad states become intolerable, i.e. worse than dead, when they last too long, but the TTO task does. The current QALY model seems to lack descriptive validity for states valued worse than dead and for states with a maimal endurable time.

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Section: Discussionsupporting

confidence: 88%

“…The unexpected gap on the negative scale could indicate that utilities derived from negative TTO boards are too negative. Third, the problem remains that it is harder to predict negative utilities than positive utilities [3,8]. This suggests that current methods to assess negative utilities need improvement.…”

Section: Discussionmentioning

confidence: 94%

The gap effect: discontinuities of preferences around dead

et al. 2005

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“…Ta ble 6 shows the in di vid u al misspec i fi ca tion of the lean mod el over the full range of health states. Some dif ferences stand out: 11211, 11112, 11113, 12223, 11131, 11133, 21232, 22331, and 33333.…”

Section: Im Pli Ca Tion For the O Rymentioning

confidence: 99%

“…In an oth er in ves ti ga tion we ex per i mented with ad just ment on the ba sis of many back ground vari ables, but the re sults hardly dif fered [6]. Tsuchiya et al [12] also found hard ly any dif fer ences (0.008 on av er age) when they weight ed the scores of so cio-de mo graph ic vari ables in their sam ple.…”

Section: Crit I Cal Ap Preasel Of Con Clu Sionsmentioning

confidence: 99%

Validating the EQ-5D with time trade off for the German population

Greiner¹,

Claes²,

et al. 2005

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The aim of this survey study was to derive the societal values of the general public for the EuroQol EQ-5D. Using the same protocol as previously used in the United Kingdom, we compared the German values with the British. In face-to-face interviews a sample of 339 individuals in northern Germany valued 15 different health states from a sample of 36 states. Values were derived using the York MVH protocol for time trade-off (TTO) and a visual analogue scale (VAS). Values for all 243 health states of the EQ-5D were estimated by a regression model. The VAS values revealed close a resemblance to the British VAS results. German TTO values were higher than the British. This was especially the case for the worse health states. The results suggest that the TTO values are more related to national variables than values derived by VAS. The use of the TTO values of this investigation makes it possible to anticipate these cultural differences in studies carried out in Germany.

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“…Previous studies of the EQ-5D index score have yielded mixed results with respect to differences generated using country-specific versus UK weights [12][13][14]. A study comparing the utility scores derived by time trade-off (TTO) techniques among German, UK and Spanish samples concluded that there were small but systematic differences between populations in the values for health states [13].…”

Section: Introductionmentioning

confidence: 98%

US and UK versions of the EQ-5D preference weights: Does choice of preference weights make a difference?

et al. 2007

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EQ-5D index scores generated using UK and US preference weights showed equivalent psychometric properties. For assessing treatment benefit in a single population, the use of either the UK or US weights as a measure of HRQOL will not change inferences. However, for comparisons across US and UK populations, the choice between these two weights should be based on their relevance to the study population.

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A comparison of EQ-5D time trade-off values obtained in Germany, The United Kingdom and Spain

Cited by 29 publications

References 0 publications

The gap effect: discontinuities of preferences around dead

The gap effect: discontinuities of preferences around dead

Validating the EQ-5D with time trade off for the German population

US and UK versions of the EQ-5D preference weights: Does choice of preference weights make a difference?

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