“…A nested case-control design was used to identify a study sample of 488 participants who were part of an already enrolled group of 900 street-recruited regular users of heroin who were participating in a study of the transition to injection and risk factors for HIV (Chitwood, Comerford, Kitner, Palacios, and Sanchez, 2001;Chitwood, Comerford, and Sanchez, 2003;Chitwood et al, 2000;Kelly and Chitwood, 2003). A stratified network-based (snowball) sample (Watters and Biernacki, 1989) of 900 non-Hispanic White, African American, and Hispanic men and women were recruited between July 1997 and February 2000 from multiple communities in south Florida known for high drug use.…”