1994
DOI: 10.1136/pgmj.70.821.195
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A comparison of intravenous and subcutaneous hydration in elderly acute stroke patients

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Cited by 61 publications
(65 citation statements)
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“…Sehen and SingerEdelstein [1] reviewed 1,850 s.c. infusions given to 270 patients in acute and long-stay geriatric beds and concluded that the s.c. route was the method of choice for adminis tering fluid to elderly patients in nonurgent situations. Other writers have reported simi lar findings [2][3][4], Lipschitz et al [7] demon strated using radioisotope tracers that normal saline (with hyaluronidase) given subcuta neously was rapidly and fully absorbed into the bloodstream.…”
Section: Discussionmentioning
confidence: 93%
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“…Sehen and SingerEdelstein [1] reviewed 1,850 s.c. infusions given to 270 patients in acute and long-stay geriatric beds and concluded that the s.c. route was the method of choice for adminis tering fluid to elderly patients in nonurgent situations. Other writers have reported simi lar findings [2][3][4], Lipschitz et al [7] demon strated using radioisotope tracers that normal saline (with hyaluronidase) given subcuta neously was rapidly and fully absorbed into the bloodstream.…”
Section: Discussionmentioning
confidence: 93%
“…For the purpose of this study, we used a continuous infusion over 24 h. Overnight infusions leave the pa tient free from restrictions by day and are par ticularly useful in patients requiring rehabili tation [4], Hyaluronidase, which breaks down s.c. tissue, increases the speed of absorption of s.c. fluids [2,7], but is not necessary in most patients.…”
Section: Discussionmentioning
confidence: 99%
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“…Finally, improved communication with young patients and their parents/caregivers is a critical factor in establishing realistic expectations and in achieving patient/parent satisfaction with the quality of medical care in the hospital and the ED. As effective as IV for fluid administration in nonemergency situations 46 Rates of fluid administration and drug absorption can be accelerated with hyaluronidase [47][48][49][50][51][52][53] Vein-sparing; fewer complications than with IV 46 Easy setup and maintenance 46,54 Cost-effective 46,54 Similar serum drug levels achieved with IO and IV 55 Access and drug delivery may be faster than with IV Risk of catheter dysfunction (eg, phlebitis, inadvertent dislodgement) 57 Risk of thrombosis 57 May take longer than other routes of venous access 56 Risk of thrombosis 56 Requires special skills that are difficult to maintain if the procedure is not done frequently Abbreviations: IV, intravenous; SC, subcutaneous; IO, intraosseous; CVC, central venous catheter.…”
Section: Discussionmentioning
confidence: 99%
“…Advantages of the SC route include the possibility of selfadministration, greater mobility for patients, it provides an alternative for patients with poor venous access and can be administered at home, away from the hospital setting [2]. Cost is another element to take into account, and several studies have shown the cost effectiveness of SC delivery over the IV drug route [3][4][5][6]. In addition, out of pocket costs for patients and their families having to take time off work and travel to hospital for IV treatment could be underestimated.…”
Section: Introductionmentioning
confidence: 99%