A comparison of inverse optimization algorithms for HDR/PDR prostate brachytherapy treatment planning

Dinkla, Anna M.; Laarse, R. van der; Kaljouw, Emmie; Pieters, Bradley R.; Koedooder, Kees; Wieringen, N. Van; Bel, Arjan

doi:10.1016/j.brachy.2014.09.006

Cited by 43 publications

(45 citation statements)

References 46 publications

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“…Underlying this is mostly a dose‐based objective function (DBOF), in which dose values below or above a certain threshold are penalized with a certain weighting factor and the most prominent tools for optimization are hybrid inverse treatment planning and optimization (HIPO) and inverse planning dose optimization by simulated annealing (IPSA) . Both are routinely used in prostate brachytherapy and well‐evaluated in different studies . Despite the lack of direct control over multiple dose‐metric objectives for each organ both methods have also been used for gynecologic applications .…”

Section: Introductionmentioning

confidence: 99%

A fast multitarget inverse treatment planning strategy optimizing dosimetric measures for high‐dose‐rate (HDR) brachytherapy

et al. 2017

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Purpose: In this study, we introduce a novel, fast, inverse treatment planning strategy for interstitial high-dose-rate (HDR) brachytherapy with multiple regions of interest solely based on dose-volumehistogram-related dosimetric measures (DMs). Methods: We present a new problem formulation of the objective function that approximates the indicator variables of the standard DM optimization problem with a smooth logistic function. This problem is optimized by standard gradient-based methods. The proposed approach is then compared against state-of-the-art optimization strategies. Results: All generated plans fulfilled prescribed DMs for all organs at risk. Compared to clinical practice, a statistically significant improvement ðp ¼ 0:01Þ in coverage of target structures was achieved. Simultaneously, DMs representing high-dose regions were significantly reduced ðp ¼ 0:01Þ. The novel optimization strategies run-time was (0.8 AE 0.3) s and thus outperformed the best competing strategies of the state of the art. In addition, the novel DM-based approach was associated with a statistically significant ðp ¼ 0:01Þ increase in the number of active dwell positions and a decrease in the maximum dwell time. Conclusions:The generated plans showed a clinically significant increase in target coverage with fewer hot spots, with an optimization time approximately three orders of magnitude shorter than manual optimization currently used in clinical practice. As optimization is solely based on DMs, intuitive, interactive, real-time treatment planning, which motivated the adoption of manual optimization in our clinic, is possible.

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Section: Introductionmentioning

confidence: 99%

A fast multitarget inverse treatment planning strategy optimizing dosimetric measures for high‐dose‐rate (HDR) brachytherapy

et al. 2017

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“…Another study comparing EGO-IIP to three other methods showed that all of them could reach the same level of compliance to clinical dose objectives. 21 User preference and expert opinion of the physician play a determinant role in the choice of optimization method.…”

Section: Resultsmentioning

confidence: 99%

Novel tools for stepping source brachytherapy treatment planning: Enhanced geometrical optimization and interactive inverse planning

et al. 2015

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“…Anatomy-based inverse optimization algorithms are already available in brachytherapy systems for clinical use [22, 23, 24, 38]. During the optimization process, the source dwell times for active source dwell positions are calculated with the aim of fulfilling thresholds for dose-volume parameters.…”

Section: Discussionmentioning

confidence: 99%

“…The two most common inverse algorithms are the HIPO (Hybrid Inverse Planning Optimization) and IPSA (Inverse Planning Simulated Annealing) [22, 23, 24]. The former uses deterministic, while the latter works with stochastic method.…”

Section: Methodsmentioning

confidence: 99%

Treatment planning for multicatheter interstitial brachytherapy of breast cancer – from Paris system to anatomy-based inverse planning

Major

Polgár

2017

jcb

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In the last decades, treatment planning for multicatheter interstitial breast brachytherapy has evolved considerably from fluoroscopy-based 2D to anatomy-based 3D planning. To plan the right positions of the catheters, ultrasound or computed tomography (CT) imaging can be used, but the treatment plan is always based on postimplant CT images. With CT imaging, the 3D target volume can be defined more precisely and delineation of the organs at risk volumes is also possible. Consequently, parameters calculated from dose-volume histogram can be used for quantitative plan evaluation. The catheter reconstruction is also easier and faster on CT images compared to X-ray films. In high dose rate brachytherapy, using a stepping source, a number of forward dose optimization methods (manual, geometrical, on dose points, graphical) are available to shape the dose distribution to the target volume, and these influence dose homogeneities to different extent. Currently, inverse optimization algorithms offer new possibilities to improve dose distributions further considering the requirements for dose coverage, dose homogeneity, and dose to organs at risk simultaneously and automatically. In this article, the evolvement of treatment planning for interstitial breast implants is reviewed, different forward optimization methods are discussed, and dose-volume parameters used for quantitative plan evaluation are described. Finally, some questions of the inverse optimization method are investigated and initial experiences of the authors are presented.

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A comparison of inverse optimization algorithms for HDR/PDR prostate brachytherapy treatment planning

Cited by 43 publications

References 46 publications

A fast multitarget inverse treatment planning strategy optimizing dosimetric measures for high‐dose‐rate (HDR) brachytherapy

A fast multitarget inverse treatment planning strategy optimizing dosimetric measures for high‐dose‐rate (HDR) brachytherapy

Novel tools for stepping source brachytherapy treatment planning: Enhanced geometrical optimization and interactive inverse planning

Treatment planning for multicatheter interstitial brachytherapy of breast cancer – from Paris system to anatomy-based inverse planning

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