A comparison of orally administered misoprostol to intravenous oxytocin for labor induction in women with favorable cervical examinations

Fassett, Michael J.; Guberman, Cristiane; Tran, Susan H; Parrish, Antigone; Guinn, Debra A.

doi:10.1016/j.ajog.2004.02.045

Cited by 18 publications

(12 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…With 50 lg vaginal misoprostol incidence of uterine contractile abnormalities have been reported to be 4.9% [5], 9% [9], 12% [1] and 26.92% in our study Ewert etal [10] observed these complications incidence as 3, 6.25, 10% with 25,100 and 200 lg controlled release vaginal inserts of misoprostol. While with 50 and 100 lg oral misoprostol uterine hyperstimulation incidence of 0.8% [5], 6.4% [11], respectively are reported. Oxytocin which has been considered safer than misoprostol [9] is also not devoid of uterine abnormalities incidence being 19.2% [12].…”

Section: Discussionmentioning

confidence: 90%

A Comparison of Vaginal vs. Oral Misoprostol for Induction of Labor–Double Blind Randomized Trial

Promila

Avasthi

Kaur

2011

J Obstet Gynecol India

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 90%

A Comparison of Vaginal vs. Oral Misoprostol for Induction of Labor–Double Blind Randomized Trial

Promila

Avasthi

Kaur

2011

J Obstet Gynecol India

View full text Add to dashboard Cite

show abstract

“…11 However, a significant limitation is that there are no randomized controlled trials (RCTs) of elective induction compared with expectant management. 18 Overall rates of vaginal delivery within 24 hours were lower with oral misoprostol (89.1% vs. 97.5%, P = 0.03). 12 High-dose oxytocin regimens are more effective than low-dose regimens in achieving a shorter duration of labor when used for induction; in most studies Pharmacologic Cervical Ripening and Labor Induction 379 the average duration of labor is shortened by approximately 0.8 to 3.4 hours.…”

Section: Oxytocinmentioning

confidence: 82%

Methods of Cervical Ripening and Labor Induction

Goetzl

2014

Clinical Obstetrics &Amp; Gynecology

View full text Add to dashboard Cite

Over the years, multiple forms and doses of pharmacologic agents have been used for cervical ripening and labor induction. This chapter will review potential criteria and article situations for choosing a particular pharmacologic agent. The discussion in this chapter will be limited to comparisons between pharmacologic agents; direct comparisons between mechanical agents and pharmacologic agents will largely be reviewed in the accompanying article: Methods of cervical ripening and labor induction: mechanical. For the purposes of this discussion, the term labor induction will be limited to patients with a "favorable cervix" by Bishop's score <6, whereas the term cervical ripening will be limited to patients with an unfavorable cervix and includes subsequent induction or augmentation of labor. Although the pharmacologic agent used for the initial cervical ripening process is the focus of this discussion, subsequent treatment with oxytocin may or may not be required for delivery.

show abstract

“…Ewert et al 14 observed these complications as 3, 6.25, 10% with 25, 100, and 200 µg controlled release vaginal inserts of misoprostol. While with 50 and 100 µg oral misoprostol, uterine hyperstimulation incidence of 0.8 6 and 6.4%, 15 respectively, are reported. Oxytocin, which has been considered safer than misoprostol, 13 is also not without uterine abnormalities, with incidence being 19.2%.…”

Section: Discussionmentioning

confidence: 99%

Comparison of 50 μg Oral and Vaginal Misoprostol Tablets in Induction of Labor at Term

Prasad¹,

Yadav²

2018

The Journal of Medical Sciences

View full text Add to dashboard Cite

Objective: To compare efficacy and safety of 50 µg misoprostol administered vaginally, with oral route for induction of labor at term. Materials and methods:One hundred women at term gestation, Bishop score ≤ 4, with various indications for labor induction were randomized. Fifty women received 50 µg misoprostol orally and 50 women received 50 µg vaginally, fourth hourly (maximum six doses) or till the women went into active labor. Results:In vaginal misoprostol group, induction delivery interval was significantly less (8.70 vs 17.47 hours) and successful induction was significantly higher (70 vs 60%) than oral group, within 24 hours of induction. In vaginal group, 46% women needed two doses for delivery compared with 8% in oral group. A maximum of six doses were required. Conclusion:Vaginal route of misoprostol is more effective in inducing labor than oral administration.

show abstract

A comparison of orally administered misoprostol to intravenous oxytocin for labor induction in women with favorable cervical examinations

Cited by 18 publications

References 17 publications

A Comparison of Vaginal vs. Oral Misoprostol for Induction of Labor–Double Blind Randomized Trial

A Comparison of Vaginal vs. Oral Misoprostol for Induction of Labor–Double Blind Randomized Trial

Methods of Cervical Ripening and Labor Induction

Comparison of 50 μg Oral and Vaginal Misoprostol Tablets in Induction of Labor at Term

Contact Info

Product

Resources

About