Spinal cord injury is a high‐cost, low‐incidence neurological disability. This condition has a significant impact on the individual, the family, health care service delivery systems, and society in general. Medical advancements have improved the likelihood of survival following spinal cord injury, and estimated life spans for persons with this condition now approach life expectancies of other people. Unfortunately, the costs associated with ongoing care and assistance escalate as financial support for these services decline. In this chapter, we review the major aspects of spinal cord injury and current information about the condition and its concomitants. We will then provide a model of adjustment and present evidence concerning the major components of the model. We consider the alternative views of adjustment, assistance and service delivery espoused by health care programs, professionals, and by consumers and their families. We conclude with an overview of intervention strategies and issues in health and public policy that affect persons with SCI.