“…Many studies have investigated problematic alcohol and recreational drug use trajectories in PLHIV, particularly in the contexts of stress, coping, and sexual risk-taking ( Glynn et al, 2019 , Mimiaga et al, 2013 , Moitra et al, 2020 , Pence et al, 2008 , Rosen et al, 2017 , Wardell et al, 2018 ). Prior studies have found that problematic alcohol consumption and recreational drug use commonly co-occur with other adverse psychosocial conditions, including depressive symptoms, loneliness, and inadequate social support ( Javanbakht et al, 2020 , Mannes et al, 2016 , Rubtsova et al, 2017 , Siconolfi et al, 2013 , Valdes et al, 2021 ). Problematic alcohol, heavy marijuana, and recreational drug use are linked to suboptimal HIV outcomes and quality of life, including sexual risk-taking, impaired cognitive function, non-adherence to HIV care recommendations, weakened immunity, and premature mortality ( American Addiction Centers, 2021 , Bensley et al, 2018 , Brown et al, 2019 , Duko et al, 2019 , Millar et al, 2017 ).…”