A comparison of three stereotactic radiotherapy techniques; ARCS vs. noncoplanar fixed fields vs. intensity modulation

Cardinale, Robert M.; Benedict, Stanley H; Wu, Qiuwen; Zwicker, Robert D.; Gaballa, H.; Mohan, Radhe

doi:10.1016/s0360-3016(98)00206-5

Cited by 159 publications

(60 citation statements)

References 14 publications

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“…Treatments can be administered by means of circular or multileaf collimator-based forward planning strategies or multileaf collimator-based inverse planning methods, with patients immobilised by frame-based or frameless techniques employing image guidance methodologies [20]. At present, several treatment planning techniques are available for linac-based SRS, but in an individual case the best choice for one or other of these techniques is not always obvious, in spite of several planning studies that have been published [21][22][23][24][25][26].…”

Section: Discussionmentioning

confidence: 99%

“…A peritumoural rind volume (PRV), defined in the current study as a 20 mm wall from the surface of the PTV, was used to evaluate and quantify healthy tissue sparing. Of interest were PRV 100 (PRV receiving >100% of the prescription dose), PRV 50 (PRV receiving >50% of the prescription dose) and PRV 25 (PRV receiving >25% of the prescription dose). A gradient score index by Meeks et al [18] and Wagner et al [19], defined as…”

Section: Evaluation Parametersmentioning

confidence: 99%

“…With a fixed collimation angle, the gradient improved by a minimum mean value of approximately 22%, corresponding to an approximate 1.3 mm change in gradient. n, number of cases; PTV, planning target volume; MLC, multileaf collimator; HD120, high-definition 120-leaf MLC; M120, millennium 120-leaf MLC; PRV, peritumoral rind volume or a 20-mm wall from the surface of the PTV; PRV 100 , PRV receiving >100% of the prescription dose; PRV 50 , PRV receiving >50% of the prescription dose; PRV 25 , PRV receiving >25% of the prescription dose.…”

Section: Mlc Width and Intracranial Srsmentioning

confidence: 99%

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Impact of the high-definition multileaf collimator on linear accelerator-based intracranial stereotactic radiosurgery

Tanyi¹,

Kato²,

Chen³

et al. 2011

BJR

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Objectives: The impact of two multileaf collimator (MLC) systems for linear accelerator-based intracranial stereotactic radiosurgery (SRS) was assessed. Methods: 68 lesions formed the basis of this study. 2.5 mm leaf width plans served as reference. Comparative plans, with identical planning parameters, were based on a 5 mm leaf width MLC system. Two collimation strategies, with collimation fixed at 0 u or 90 u and optimised per arc or beam, were also assessed. Dose computation was based on the pencil beam algorithm with allowance for tissue heterogeneity. Plan normalisation was such that 100% of the prescription dose covered 95% of the planning target volume. Plan evaluation was based on target coverage and normal tissue avoidance criteria. Results: The median conformity index difference between the MLC systems ranged between 0.8% and 14.2%; the 2.5 mm MLC exhibited better dose conformation. The median reduction of normal tissue exposed to >100%, >50% and >25% of the prescription dose ranged from 13.4% to 29.7%, favouring the 2.5 mm MLC system. Dose fall-off was steeper for the 2.5 mm MLC system with an overall median absolute difference ranging from 0.4 to 1.2 mm. The use of collimation optimisation resulted in a decrease in differences between the MLC systems. The results demonstrated the dosimetric merit of the 2.5 mm leaf width MLC system over the 5 mm leaf width system, albeit small, for the investigated range of intracranial SRS targets. Conclusion:The clinical significance of these results warrants further investigation to determine whether the observed dosimetric advantages translate into outcome improvements.

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Section: Discussionmentioning

confidence: 99%

Section: Evaluation Parametersmentioning

confidence: 99%

Section: Mlc Width and Intracranial Srsmentioning

confidence: 99%

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Impact of the high-definition multileaf collimator on linear accelerator-based intracranial stereotactic radiosurgery

Tanyi¹,

Kato²,

Chen³

et al. 2011

BJR

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“…This capability makes it possible to give a high dose to the target volume while sparing adjacent normal tissues. Studies have shown benefits of IMRT in the treatment of head-andneck [6][7][8][9][10][11][12][13] and other cancers [14][15][16][17][18][19][20] . The conventional technique for esophageal cancer is to use initial anterior-posterior large field arrangement followed by multi-field technique to boost the primary tumor with field size reduction.…”

Section: Introductionmentioning

confidence: 99%

Comparison of conformal and intensity-modulated techniques for simultaneous integrated boost radiotherapy of upper esophageal carcinoma

Fu¹,

Wang²,

Zhou³

et al. 2004

WJG

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AIM:To compare intensity-modulated radiotherapy (IMRT) with conformal radiotherapy (CRT) by investigating the dose profiles of primary tumors, electively treated regions, and the doses to organs at risk. METHODS:CRT and IMRT plans were designed for five patients with upper esophageal carcinoma. For each patient, target volumes for primary lesions (67.2 Gy) and electively treated regions (50.4 Gy) were predefined. An experienced planner manually designed one CRT plan. Four IMRT plans were generated with the same dose-volume constraints, but with different beam arrangements. Indices including dose distributions, dose volume histograms (DVHs) and conformity index were compared. RESULTS:The plans with three intensity-modulated beams were discarded because the doses to spinal cord were lager than the tolerable dose 45Gy, and the dose on areas near the skin was up to 50Gy. When the number of intensity beams increased to five, IMRT plans were better than CRT plans in terms of the dose conformity and homogeneity of targets and the dose to OARs. The dose distributions changed little when the beam number increased from five to seven and nine. CONCLUSION:IMRT is superior to CRT for the treatment of upper esophageal carcinoma with simultaneous integrated boost (SIB). Five equispaced coplanar intensity-modulated beams can produce desirable dose distributions. The primary tumor can get higher equivalent dose by SIB technique. The SIB-IMRT technique shortens the total treatment time, and is an easier, more efficient, and perhaps a less errorprone way in delivering IMRT.Fu WH, Wang LH, Zhou ZM, Dai JR, Hu YM, Zhao LJ. Comparison of conformal and intensity-modulated techniques for simultaneous integrated boost radiotherapy of upper esophageal carcinoma.

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“…Os MLCs, além de substituírem os blocos para conformação dos campos de radiação, permitem a realização de técnicas especiais de radioterapia como o arco dinâmico [23,24] e a radioterapia de intensidade modulada -IMRT [5] . Os benefícios e a complexidade advindos dessa capacidade têm levado à criação de novos protocolos de tratamento, fornecendo potencial para um controle maior das várias patologias tratadas.…”

Section: Colimadores Multi-lâminas -Mlcunclassified

Dosimetria dos sistemas de radiocirurgia estereotáxica com aceleradores lineares equipados com colimadores micro multi-lâminas

Vieira¹

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A comparison of three stereotactic radiotherapy techniques; ARCS vs. noncoplanar fixed fields vs. intensity modulation

Cited by 159 publications

References 14 publications

Impact of the high-definition multileaf collimator on linear accelerator-based intracranial stereotactic radiosurgery

Impact of the high-definition multileaf collimator on linear accelerator-based intracranial stereotactic radiosurgery

Comparison of conformal and intensity-modulated techniques for simultaneous integrated boost radiotherapy of upper esophageal carcinoma

Dosimetria dos sistemas de radiocirurgia estereotáxica com aceleradores lineares equipados com colimadores micro multi-lâminas

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