A complex choristoma presenting as a salmon patch lesion in the bulbar conjunctiva

Abstract

PurposeWe describe a rare case of a complex choristoma appearing as a salmon-patch lesion in the nasal conjunctiva. While benign, complex choristomas are grossly indistinguishable from malignant lesions, and an excisional biopsy is warranted to confirm the diagnosis.ObservationsA 31-year-old man presented with an elevated glistening pink mass on the conjunctiva. An excisional biopsy with a “no-touch” technique was performed, followed by placement of an amniotic membrane graft without postoperative complications. No subsequent medical treatment was pursued after the biopsy and histopathologic evaluation. Histopathology confirmed a diagnosis of a complex choristoma with sections consisting of fibroadipose tissue with cartilage, smooth muscle, and nerves. Histopathology was negative for malignant cells without morphologic evidence of a lymphoma.Conclusions and ImportanceConjunctival tumors are difficult to distinguish clinically, and a differential diagnosis often includes the possibility of a malignancy. Histopathologic diagnosis may be required to distinguish between various entities. In our case, a salmon-patch conjunctival tumor was biopsied and confirmed to be a benign complex choristoma.

Epibulbar simple cartilaginous choristoma associated with unique pigmented multicystic component

“…5 In contrast, Oh et al reported a case of complex cartilaginous choristoma presenting as a salmon-patch lesion in the nasal epibulbar area with superficial vascularization and no corneal involvement. 7 Our report features a epibulbar lesion with multiple pigmented cysts, which has not been reported previously in association with a cartilaginous choristoma. The cysts were not characteristic of those typically seen as part of a cystic nevus, as they were larger and more numerous.…”

“…In most reported cases, the cartilage is part of a complex choristoma that also includes other components such as lacrimal gland tissue, nerves, and smooth muscle. 2,5–7 Such complex choristomas may be part of syndromes including the organoid nevus syndrome or the nevus sebaceous of Jadassohn. 2 Furthermore, while most lesions involve the epibulbar space, non-epibulbar regions such as the eyelid have also been reported.…”

Intraspinal choristoma in the lumbar region: A case report

“…[ 1 ] While it can occur anywhere in the body, it is more frequently observed in the head and neck region, especially in the pituitary gland [ 2 ] and oral cavity. [ 3 ] Intraspinal choristomas are rare and, to the best of our knowledge, only 2 cases have been reported. [ 4 , 5 ] Thus, it is pretty rare for choristoma to occur in the spinal canal.…”