A comprehensive management protocol to treat cleft maxillary hypoplasia

Richardson, Sunil; Krishna, Shreya; Khandeparker, Rakshit Vijay Sinai

doi:10.1016/j.jcms.2017.12.005

Cited by 30 publications

(36 citation statements)

References 28 publications

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“…Cleft lip and palate repair and revisions can also lead to serious functional detriment. Maxillary hypoplasia, or underdevelopment of the maxillary bone leading to a reduction in its dimensions along all axes, is the most common secondary deformity as a result of cleft lip/palate and their initial repair (Richardson et al, 2018) (Figure 3). Maxillary hypoplasia is thought to be due to a combination of intrinsic primary growth deficiency of the maxilla and fibrosis of the lip and palate resulting from surgery (Oberoi et al, 2012; Richardson et al, 2018).…”

Section: Clinical Correlate: Cleft Lip and Palatementioning

confidence: 99%

“…Maxillary hypoplasia, or underdevelopment of the maxillary bone leading to a reduction in its dimensions along all axes, is the most common secondary deformity as a result of cleft lip/palate and their initial repair (Richardson et al, 2018) (Figure 3). Maxillary hypoplasia is thought to be due to a combination of intrinsic primary growth deficiency of the maxilla and fibrosis of the lip and palate resulting from surgery (Oberoi et al, 2012; Richardson et al, 2018). Specifically, the formation of stiff, fibrotic scar tissue following the primary repair operation is believed to impair maxillary blood supply and to physically tether the developing maxilla, restricting its anterior and lateral growth (James and Brook, 1985).…”

Section: Clinical Correlate: Cleft Lip and Palatementioning

confidence: 99%

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The Spectrum of Scarring in Craniofacial Wound Repair

et al. 2019

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Fibrosis is intimately linked to wound healing and is one of the largest causes of wound-related morbidity. While scar formation is the normal and inevitable outcome of adult mammalian cutaneous wound healing, scarring varies widely between different anatomical sites. The spectrum of craniofacial wound healing spans a particularly diverse range of outcomes. While most craniofacial wounds heal by scarring, which can be functionally and aesthetically devastating, healing of the oral mucosa represents a rare example of nearly scarless postnatal healing in humans. In this review, we describe the typical wound healing process in both skin and the oral cavity. We present clinical correlates and current therapies and discuss the current state of research into mechanisms of scarless healing, toward the ultimate goal of achieving scarless adult skin healing.

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Section: Clinical Correlate: Cleft Lip and Palatementioning

confidence: 99%

Section: Clinical Correlate: Cleft Lip and Palatementioning

confidence: 99%

The Spectrum of Scarring in Craniofacial Wound Repair

et al. 2019

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“…Scar formation occurs when normal physiological process is not achieved. Most oral wounds do not cause serious scars; however, fibrosis can occur when healthy bone does not support the base of the wound, such as in congenital defects, lip clefts, and/or palate clefts [ 33 ]. Additionally, a persistent inflammation in the chronic wound can result in delayed healing and fibrosis [ 16 ].…”

Section: Complications After Periodontal Treatmentmentioning

confidence: 99%

Periodontal Wound Healing and Tissue Regeneration: A Narrative Review

et al. 2021

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Periodontal disease is a major public health issue, and various periodontal therapies have been performed to regenerate periodontal tissues. The periodontium is a complex structure composed of specialized tissues that support the teeth, and most periodontal surgeries are invasive procedures, including a resection of the gingiva or the alveolar bone. The periodontal wound healing process is slightly different from cutaneous wound healing and is similar to fetal healing, being almost scar-free. The aim of this review article is to provide an overview of periodontal wound healing and discuss various surgical and pharmaceutical approaches to achieve stable wound healing and improve the treatment outcomes. In addition, detrimental and limiting factors that induce a compromised prognosis are discussed, along with the perspective and future direction for successful periodontal tissue regeneration.

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“…Richardson et al [60] examined all relapse cases among individuals where more than 11 mm of maxillary advancement was applied, and they reported a horizontal relapse rate of 18.75%. Nevertheless, Bhatia et al [61] concluded that relapse rates stayed the same even in maxillary advancement degrees of more than 15 mm (mostly in cleft patients).…”

Section: Success Of Orthognathic Surgerymentioning

confidence: 99%

Orthognathic Surgery in Cleft Lip and Palate Patients

Yılmaz¹,

Demirkaya²

2020

Current Treatment of Cleft Lip and Palate

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Cleft lip and palate patients often exhibit severe dentofacial deformities that necessitate orthognathic surgery. Orthognathic surgery in these patients generally includes not only maxillary advancement, but also sagittal, horizontal, and vertical movement of both jaws. Surgical planning and execution presents many difficulties, caused by the presence of extensive scar tissues from previous surgeries, tissue deficiencies, the difficulty of aligning multiple segments of bone and soft tissues. Other challenges in cleft patients are complications related to post-surgical airway, speech, velopharyngeal insufficiency, nerve damage, and infections. This review is focused on orthognathic surgery in cleft lip and palate patients, management, techniques, success, and complications.

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A comprehensive management protocol to treat cleft maxillary hypoplasia

Cited by 30 publications

References 28 publications

The Spectrum of Scarring in Craniofacial Wound Repair

The Spectrum of Scarring in Craniofacial Wound Repair

Periodontal Wound Healing and Tissue Regeneration: A Narrative Review

Orthognathic Surgery in Cleft Lip and Palate Patients

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