A Comprehensive Review of Pediatric Glaucoma Following Cataract Surgery and Progress in Treatment

Abstract

Glaucoma following cataract surgery (GFCS) remains a serious postoperative complication of pediatric cataract surgery. Various risk factors, including age at lensectomy, intraocular lens implantation, posterior capsule status, associated ocular/systemic anomaly, additional intraocular surgery, and a family history of congenital cataract and GFCS, have been reported. However, the optimal surgical approach remains unclear. This review evaluates the diagnostic criteria, classification, risk factors, mechanism, and surgical management, especially the efficacy of minimally invasive glaucoma surgery, in GFCS, and aims to propose an optimal clinical management strategy for GFCS. The results of our review indicate that ab interno trabeculotomy (goniotomy) may be the most appropriate first-line treatment for GFCS.

Outcomes of Goniotomy With or Without Secondary Intraocular Lens Implantation in Pediatric Glaucoma Following Cataract Surgery: A Prospective Pilot Study

“…Congenital and infantile cataract is an important and preventable cause of childhood blindness in which timely surgical intervention with cataract extraction is key to the visual outcome. Nevertheless, glaucoma following cataract surgery (GFCS) is one of the most serious and sight-threatening complications after pediatric cataract surgery 1 . The reported incidence of GFCS varied from 0% to 45% of eyes 2,3 .…”

“…The management of GFCS is difficult. Although multiple modalities of treatment are available, the visual prognosis remains guarded 1–3 …”

“…Nevertheless, glaucoma following cataract surgery (GFCS) is one of the most serious and sightthreatening complications after pediatric cataract surgery. 1 The reported incidence of GFCS varied from 0% to 45% of eyes. 2,3 The management of GFCS is difficult.…”

“…Although multiple modalities of treatment are available, the visual prognosis remains guarded. [1][2][3] Surgical intervention is important for the management of GFCS to achieve satisfactory intraocular pressure (IOP) control. Chen et al 4 reported in a retrospective review of 170 eyes with GFCS that 57.1% of eyes underwent 1 or more glaucoma surgery for IOP control.…”

Secondary in-the-bag intraocular lens implantation combined with 120- and 360-degree goniotomy in glaucoma following congenital cataract surgery: a case report

“…G laucoma following cataract surgery (GFCS) is one of the most sight-threatening postoperative complications of pediatric cataract surgery, and often becomes refractory to medical treatment [1] . Goniotomy has been an increasingly popular procedure for primary open angle glaucoma and primary angle-closure glaucoma with 120-, 240-, or 360-degree [2] .…”