2017
DOI: 10.1007/s13534-017-0053-0
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A computational model of ureteral peristalsis and an investigation into ureteral reflux

Abstract: The aim of this study is to create a computational model of the human ureteral system that accurately replicates the peristaltic movement of the ureter for a variety of physiological and pathological functions. The objectives of this research are met using our in-house fluidstructural dynamics code (CgLes-Y code). A realistic peristaltic motion of the ureter is modelled using a novel piecewise linear force model. The urodynamic responses are investigated under two conditions of a healthy and a depressed contra… Show more

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Cited by 19 publications
(20 citation statements)
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“…As already noted, two types of FSI problems are investigated: submerged vegetation in a channel flow and kinetic turbine rotors. The FSI code has already been extensively verified in previous publications [10,[18][19][20][21][22][23], and thus, only verifications specific to the class of the investigated cases are shown followed by results of interest.…”
Section: Results and Analysismentioning
confidence: 99%
See 1 more Smart Citation
“…As already noted, two types of FSI problems are investigated: submerged vegetation in a channel flow and kinetic turbine rotors. The FSI code has already been extensively verified in previous publications [10,[18][19][20][21][22][23], and thus, only verifications specific to the class of the investigated cases are shown followed by results of interest.…”
Section: Results and Analysismentioning
confidence: 99%
“…An IBM algorithm ties the two solvers together. This FSI methodology has already been successfully implemented for a range of problems from bio-fluids of red blood cells flow [18,19] and urine flow in the ureter [20] to sediment [21,22] and marine tidal turbines [10]. In this section, the main points of the method are highlighted, where further details are given in Refs.…”
Section: Methodsmentioning
confidence: 99%
“…There are growing interests on studies of peristalsis of non-Newtonian fluid flows due to their fundamental importance in physiological, engineering, industrial and medical applications. In biological process, such motion occurs in movement of chyme in gastrointestinal tract 1 , circulation of blood in arterioles 2 , passage of urine in ureters 3 , passage of ovum in the fallopian tube 4 , swallowing food via esophagus 5 and so on. Important characteristics of peristalsis of viscous fluid is initially studied by Latham 6 and Shapiro et al 7 , they examined peristalsis of viscous fluid in channel/tube under lubrication approaches.…”
mentioning
confidence: 99%
“…It much reduces the complexity of the simulation while Quadrio et al 24 argued for its effect to be small on the result, although it can be of importance in people who have cartilage weakness, trauma or high abutment of the lateral crus to the pyriform aperture. The computational technology to simulate the flow-structure interaction for bio-fluid applications exists as was done for the human ureter 25 . It requires good knowledge of the wall structural properties and thus is left for a future study.…”
Section: Computational Methodologymentioning
confidence: 99%