A Computerized Microstereotactic Method to Approach, 3-DimensionaIIy Reconstruct, Remove and Adjuvantly Treat Small CNS Lesions

Abstract

The authors update a novel method recently utilized in humans with various CNS pathology for stereotactic localization, removal, and adjuvant therapy of small CNS lesions using additional computer processing of the data from a GE 8800 CT Scanner. Multiple computer algorithms developed at Cal Tech enhance regions of interest by filtering, magnifying, color-coding and 3-dimensional reconstruction based on routine CT scans. This stereotactic approach is calculated by the computer and coordinates are mated to a modified head fixation system; small lesions can be removed with the apparatus described herein under direct binocular vision with minimal tissue damage. This technique may offer the possibility of successful secondary application of adjuvant therapy to, particularly, a CNS glioma site.

A Computer-Assisted Device for the Intraoperative CT-Correlated Localization of Brain Tumors

“…Jacques et al [4] mounted an operating endoscope onto a heavy stereotactic frame and, guided by CT data, were able to operate microsurgically on small supratentorial brain tumors with a high degree of accuracy. The most advanced system is the Mayo ste reotactic operation suite' devised by Kelly and his team [5][6][7][8], which integrates a large stereotactic frame with a directly mounted operating microscope, a sophisticated imag ing system for CT, MRI and angiographic data and an interactive CO2 laser scanner for automatic tumor resection.…”

Modern principles of stereotactic neurosurgery of nontraumatic intracerebral hematomas: a literature review

“…Оригинальный способ микростереотаксической хирургии при наличии небольших очагов поражения (в частности, НВМГ) предложен S.Jacques и соавторами [62][63][64]. Cтереотаксические расчеты проводили по данным КТ с одновременной трехмерной цветной реконструкцией очага поражения.…”

Stereotactic Neurosurgery and Computerized Tomographic Scanning

“…The head fixation system includes a binocular endoscope which can be directed by the stereotactic frame to remove or treat small CNS lesions [26,27,49,50].…”

“…This information may be used to plan surgery, which may involve removal through an endoscope [26,27,49,50]. Alternatively, multiple stereotactic radiofrequency lesions [20] or laser [28] may be used to treat the tumor.…”

“…The three dimensional definition of the lesion may be used [26,27,49,50] so that calculations may be made by computer for optimally po sitioned, stereotactically inserted radioisotope [40], or three-dimen sional reconstruction can be used to calculate optimal radiation from external sources.…”