A Computerized System That Uses High-frequency Data for Analysis of Myocardial Contrast Echocardiograms

Jong, Nico de; Mittertreiner, Wim H.; Ligtvoet, Kees M.; Cate, Folkert J. Ten

doi:10.1016/s0894-7317(14)80502-6

Cited by 5 publications

(1 citation statement)

References 5 publications

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“…However, when imaging air-filled microbubbles, the nonlinear factors (harmonics) impact the amplitude of the scattering properties. These acoustic factors include 1) medium properties: surface tension, viscosity, thermal transfers, and liquid and gas vapor pressures; 2) gas properties: molecular weight and gas solubility; 3) shell properties: elastic modulus, thickness, and damping effects; 4) ultrasound transceiver: high-speed digital interfaces (16,84,85), harmonics (70,71,90), and ultra-and subharmonics (10).…”

Section: Microbubble Acousticsmentioning

confidence: 99%

The powerful microbubble: from bench to bedside, from intravascular indicator to therapeutic delivery system, and beyond

Feinstein

2004

American Journal of Physiology-Heart and Circulatory Physiology

206

150

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This review discusses the development, current applications, and therapeutic potential of ultrasound contrast agents. Microbubbles containing gases act as true, intravascular indicators, permitting a noninvasive, quantitative analysis of the spatial and temporal heterogeneity of blood flow and volumes within the microvasculature. These shelled microbubbles are near-perfect reflectors of acoustic ultrasound energy and, when injected intravenously into the bloodstream, reflect ultrasound waves within the capillaries without disrupting the local environment. Accordingly, microbubble ultrasound contrast agents are clinically useful in enhancing ultrasound images and improving the accuracy of diagnoses. More recently, ultrasound contrast agents have been used to directly visualize the vasa vasorum and neovascularization of atherosclerotic carotid artery plaques, thus suggesting a new paradigm for diagnosis and treatment of atherosclerosis. Future applications of these microscopic agents include the deliver of site-specific therapy to targeted organs in the body. Medical therapies may use these microbubbles as carriers for newer therapeutic options.

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Section: Microbubble Acousticsmentioning

confidence: 99%

The powerful microbubble: from bench to bedside, from intravascular indicator to therapeutic delivery system, and beyond

Feinstein

2004

American Journal of Physiology-Heart and Circulatory Physiology

206

150

View full text Add to dashboard Cite

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The angle of incidence of the ultrasonic beam: A critical factor for the image quality in intravascular ultrasonography

Mario

Madretsma

Linker

et al. 1993

American Heart Journal

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The effects of the angle of incidence of the ultrasound beam on the image quality were studied in 21 pressurized arterial specimens examined with a 30 MHz intravascular ultrasonographic catheter. When the ultrasonographic catheter was in an eccentric position in the vessel lumen, the videodensity of the segments of the vessel wall with the least favorable angle of interrogation (a shift of 49 +/- 6 degrees from the tangent to the tissue surface) was 27% +/- 19% lower than the videodensity measured with the catheter in the center of the lumen. When the catheter was placed in a position that was not parallel to the long axis of the vessel, a further decrease was observed, especially in the vessel wall opposite the position of the catheter. An artificial dissection was induced in eight specimens. Dropouts that involved the dissection plane and the underlying structures were produced with positions of the echographic catheter inducing a narrow angle between ultrasound beam and dissection plane. These experimentally induced artifacts were compared with similar findings from the in vivo evaluation of peripheral and coronary arteries. The angle of incidence of the ultrasound beam is a major determinant of the image quality in intravascular ultrasonography. Angle-dependent artifacts occur with eccentric and noncoaxial positions of the ultrasonographic catheter and, in particular, with imaging of large intraluminal dissections. Awareness of this problem may prevent image misinterpretation and has relevance for future improvement of catheter technology and design.

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Volumetric arterial flow quantification using echo contrast. An in vitro comparison of three ultrasonic intensity methods: Radio frequency, video and doppler

Schwarz

Bezante

Chen

et al. 1993

Ultrasound in Medicine & Biology

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A Computerized System That Uses High-frequency Data for Analysis of Myocardial Contrast Echocardiograms

Cited by 5 publications

References 5 publications

The powerful microbubble: from bench to bedside, from intravascular indicator to therapeutic delivery system, and beyond

The powerful microbubble: from bench to bedside, from intravascular indicator to therapeutic delivery system, and beyond

The angle of incidence of the ultrasonic beam: A critical factor for the image quality in intravascular ultrasonography

Volumetric arterial flow quantification using echo contrast. An in vitro comparison of three ultrasonic intensity methods: Radio frequency, video and doppler

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