Electronic learning (e-learning) platform is fast growing in the Africa educational system and many students are busy enrolling and accepting it as a means for educational advancement and career achievement channel. An e-learning platform handles students across different cultural settings with various perceptions, learning needs and expectations. Nonetheless, incorporating cultural differences, expectations and perceptions as well as managing them, is challenging on the side of e-learning developers. The challenging aspect of the cultural management of e-learning can be attributed to the software crisis which has lasted for decades now with little or no solution to it. This study tries to understand and determine the perception of students on the development of a culture-oriented e-learning system that can allow them to be able to customise it to suit desired features in their home language at all times. The study also determines the factors and components that necessitate the implementation of the culture-oriented e-learning system. This study was carried out using quantitative research method among the students of NorthWest University, South Africa with a total number of 728 questionnaires collected and analysed. The perception of the involved students was mixed in the sense that some of them preferred to use English language as a medium of learning in e-learning while others would like the e-learning system platform to be designed and developed between their home language and English language. Again, their challenges range from lack of engagement to the inflexible e-learning system leading to the discovering of factors that facilitate culture-oriented e-learning system.