A Concise Review of the Antibacterial Action of Gold Nanoparticles Against Various Bacteria

Ifijen, Ikhazuagbe H.; Maliki, Muniratu; Udokpoh, Nyaknno U.; Odiachi, Ifeanyi J.; Atoe, Best

doi:10.1007/978-3-031-22524-6_58

Cited by 15 publications

(8 citation statements)

References 44 publications

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“… 43 , 212 Secondly, Ag and Au NPs synthesized by green synthesis approach frequently demonstrate excellent biocompatibility, indicating their compatibility with biological systems. 213 In comparison to their counterparts made using conventional synthesis methods, NPs synthesized via green synthesis techniques frequently use non-toxic or low-toxic ingredients. 214 , 215 Au NPs synthesized through green synthesis approach possess better stability, allowing them to hold onto their characteristics and effectiveness for longer periods of time.…”

Section: Advantages Of Biomedical Applications Of Green Synthesized A...mentioning

confidence: 99%

Recent Advancements and Unexplored Biomedical Applications of Green Synthesized Ag and Au Nanoparticles: A Review

Ahmad,

Ali

et al. 2024

IJN

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Green synthesis of silver (Ag) and gold (Au) nanoparticles (NPs) has acquired huge popularity owing to their potential applications in various fields. A large number of research articles exist in the literature describing the green synthesis of Ag and Au NPs for biomedical applications. However, these findings are scattered, making it time-consuming for researchers to locate promising advancements in Ag and Au NPs synthesis and their unexplored biomedical applications. Unlike other review articles, this systematic study not only highlights recent advancements in the green synthesis of Ag and Au NPs but also explores their potential unexplored biomedical applications. The article discusses the various synthesis approaches for the green synthesis of Ag and Au NPs highlighting the emerging developments and novel strategies. Then, the article reviews the important biomedical applications of green synthesized Ag and Au NPs by critically evaluating the expected advantages. To expose future research direction in the field, the article describes the unexplored biomedical applications of the NPs. Finally, the articles discuss the challenges and limitations in the green synthesis of Ag and Au NPs and their biomedical applications. This article will serve as a valuable reference for researchers, working on green synthesis of Ag and Au NPs for biomedical applications.

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Section: Advantages Of Biomedical Applications Of Green Synthesized A...mentioning

confidence: 99%

Recent Advancements and Unexplored Biomedical Applications of Green Synthesized Ag and Au Nanoparticles: A Review

Ahmad,

Ali

et al. 2024

IJN

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“…Analysis of AuNP's antibacterial activity has also been a hot topic in modern times. AuNP has been shown to have an acceptable performance against a variety of infections [ 68 ]. Dental caries, gum disease, tissue engineering, dental implantology, and cancer diagnostics have all been studied using AuNPs.…”

Section: Metal Nanoparticles In Periodontitismentioning

confidence: 99%

Recent advances in metal nanoparticles to treat periodontitis

Nasiri,

Masoumi,

Amini

et al. 2023

J Nanobiotechnol

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The gradual deterioration of the supporting periodontal tissues caused by periodontitis, a chronic multifactorial inflammatory disease, is thought to be triggered by the colonization of dysbiotic plaque biofilms in a vulnerable host. One of the most prevalent dental conditions in the world, periodontitis is now the leading factor in adult tooth loss. When periodontitis does develop, it is treated by scraping the mineralized deposits and dental biofilm off the tooth surfaces. Numerous studies have shown that non-surgical treatment significantly improves clinical and microbiological indices in individuals with periodontitis. Although periodontal parameters have significantly improved, certain bacterial reservoirs often persist on root surfaces even after standard periodontal therapy. Periodontitis has been treated with local or systemic antibiotics as well as scaling and root planning. Since there aren't many brand-new antibiotics on the market, several researchers are currently concentrating on creating alternate methods of combating periodontal germs. There is a delay in a study on the subject of nanoparticle (NP) toxicity, which is especially concerned with mechanisms of action, while the area of nanomedicine develops. The most promising of them are metal NPs since they have potent antibacterial action. Metal NPs may be employed as efficient growth inhibitors in a variety of bacteria, making them useful for the treatment of periodontitis. In this way, the new metal NPs contributed significantly to the development of efficient anti-inflammatory and antibacterial platforms for the treatment of periodontitis. The current therapeutic effects of several metallic NPs on periodontitis are summarized in this study. This data might be used to develop NP-based therapeutic alternatives for the treatment of periodontal infections. Graphical Abstract

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“…They are characterized by their excellent optical characteristics and substantial electric field enhancement, enabling their prospective use in bioimaging, sensors, and therapies . Metal NPs have emerged as promising candidates for controlling biofilms due to their physicochemical properties. , Several studies have reported the anti-biofilm activity of metal NPs against a wide range of bacterial pathogens . Silver, gold, zinc, copper, and iron NPs have been extensively investigated for their anti-biofilm potential .…”

Section: Nanotechnological Approaches For Biofilm Controlmentioning

confidence: 99%

“… 90 Metal NPs have emerged as promising candidates for controlling biofilms due to their physicochemical properties. 91 , 92 Several studies have reported the anti-biofilm activity of metal NPs against a wide range of bacterial pathogens. 93 Silver, gold, zinc, copper, and iron NPs have been extensively investigated for their anti-biofilm potential.…”

Section: Nanotechnological Approaches For Biofilm Controlmentioning

confidence: 99%

Advances in Nanotechnology for Biofilm Inhibition

et al. 2023

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Biofilm-associated infections have emerged as a significant public health challenge due to their persistent nature and increased resistance to conventional treatment methods. The indiscriminate usage of antibiotics has made us susceptible to a range of multidrug-resistant pathogens. These pathogens show reduced susceptibility to antibiotics and increased intracellular survival. However, current methods for treating biofilms, such as smart materials and targeted drug delivery systems, have not been found effective in preventing biofilm formation. To address this challenge, nanotechnology has provided innovative solutions for preventing and treating biofilm formation by clinically relevant pathogens. Recent advances in nanotechnological strategies, including metallic nanoparticles, functionalized metallic nanoparticles, dendrimers, polymeric nanoparticles, cyclodextrin-based delivery, solid lipid nanoparticles, polymer drug conjugates, and liposomes, may provide valuable technological solutions against infectious diseases. Therefore, it is imperative to conduct a comprehensive review to summarize the recent advancements and limitations of advanced nanotechnologies. The present Review encompasses a summary of infectious agents, the mechanisms that lead to biofilm formation, and the impact of pathogens on human health. In a nutshell, this Review offers a comprehensive survey of the advanced nanotechnological solutions for managing infections. A detailed presentation has been made as to how these strategies may improve biofilm control and prevent infections. The key objective of this Review is to summarize the mechanisms, applications, and prospects of advanced nanotechnologies to provide a better understanding of their impact on biofilm formation by clinically relevant pathogens.

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A Concise Review of the Antibacterial Action of Gold Nanoparticles Against Various Bacteria

Cited by 15 publications

References 44 publications

Recent Advancements and Unexplored Biomedical Applications of Green Synthesized Ag and Au Nanoparticles: A Review

Recent Advancements and Unexplored Biomedical Applications of Green Synthesized Ag and Au Nanoparticles: A Review

Recent advances in metal nanoparticles to treat periodontitis

Advances in Nanotechnology for Biofilm Inhibition

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