This paper presents a comparative study on the effect of statistical dopant fluctuations on threshold voltage (V th ) of emerging and conventional metal-oxide-semiconductor (MOS) field-effect (FET) transistors (MOSFETs). In this context, three n-channel MOSFET structures representing three different complementary MOS (CMOS) technologies at the 20 nm node are considered. The structures represent a conventional device with symmetric halo or pocket regions around the n + source-drain formed by a single p-type dopant implantation; a second conventional device with symmetric p-type halo regions around the n + source-drain formed by multiple p-type dopant implantations; and an emerging epitaxial-channel device with symmetric p-type halo regions around the n + source-drain where the halo regions are formed by up-diffusion of multiple p-type buried layers from the bulk-substrate during epitaxy. For these devices, the values of V th variance and mismatch are computed as a function of device dimensions. The results show that the multiple-halo devices, in general, offer significantly lower V th variance and mismatch compared to the conventional single-halo devices whereas, the emerging epitaxial-channel multiple-halo MOSFETs offer the lowest V th variability compared to the conventional devices at the same technology node. And, the value of the mismatch coefficient for the emerging technology is about 0.68 mV × µm compared to that of 1.33 and 1.07 mV × µm for the conventional single-halo and multiple-halo technologies, respectively. This study, clearly, demonstrates the benefit of the emerging epitaxial-channel buried-halo MOSFETs in significantly reducing the effect of statistical dopant fluctuations on V th at the advanced planar CMOS technology nodes.