A cyto-histopathological correlation study of lesions of uterine cervix

Tengli, Mandakini B.; Ahmed, Mohammed Mateen

doi:10.5958/2394-6792.2016.00055.7

Cited by 2 publications

(1 citation statement)

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“…Liquid based pap cytology test was not performed. In this study, squamous-intraepithelial lesion was observed in 3.33% and invasive cancer in 73.3% respectively 3,4 (MB Tengli, 2016 & Edwardo L. Franco et al, 2001) which is different from studies conducted in other non-gynaecological centres. In contrast, a population-based study by Meisels and Morin 5 (1985), revealed squamous intraepithelial lesion in 0.32% and invasive cancer in 0.05% of cases only.…”

Section: Discussioncontrasting

confidence: 69%

Clinical, Cytological and Histopathological Correlation in Lesions of Uterine Cervix

Parija¹,

Mohapatra²

2017

jemds

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BACKGROUNDCytological screening of the uterine cervix by Papanicolaou test has reduced the incidence of cervical cancer. But cytological diagnosis in clinically suspicious lesions of cervix is provisional and has to be corroborated with histopathological findings for effective treatment response. MATERIALS AND METHODSStudy Design-A descriptive study. Three hundred patients attending Gynaecological Oncology OPD of A.H. Regional Cancer Centre, Cuttack during the period April 2016-March 2017, were studied. History taking, clinical examination was followed by cervical smear and multiple punch biopsies, in patients with unhealthy cervix. The cytological and histopathological results were correlated with each other and clinically. RESULTSClinically, cancer was detected in 77.6% cases. Cytologically, 73.3% reported carcinoma and 3.33% squamous intraepithelial lesions. Histopathologically, 74.6% showed carcinoma and 3.7% SIL. The cytohistopathological agreement was 69.2% in inflammatory lesions and 90.5% in invasive carcinomas. In clinically unhealthy cervix, a report of squamous intraepithelial-lesion by cytology was seen in 17.02% and by histopathology was found in 19.15%. Cytological proof of cancer was obtained in 73.3% of cases and histopathological proof in 74%. On overall analysis of 300 cases of suspicious cervix, 229 correlated well with cytology, labelling them as abnormal and 246 cases were stamped as diseased by histopathology. CONCLUSIONThis study proves that cytology can be used as a very effective screening tool to catch high risk cases, which can be biopsied to detect cancer early. Both cytology and histopathology correlate well with clinically obvious lesions of the cervix.

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Section: Discussioncontrasting

confidence: 69%

Clinical, Cytological and Histopathological Correlation in Lesions of Uterine Cervix

Parija¹,

Mohapatra²

2017

jemds

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Profile of utero-cervical lesions in peri- & post-menopausal women in Kumaon Region of Uttarakhand: An Institutional study

Pratap

Joshi²,

Thapliyal³

et al. 2017

IJMSCI

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INTRODUCTION PAP smear is an important tool which compliment histopathology in detection of various cervical lesions. Since last few decades, it is becoming easy and cost-effective way for early detection of pre-cancerous and cancerous cervical lesions. AIMS/OBJECTIVES: The objective of this study is to evaluate the utero-cervical lesions in peri-& post-menopausal age group by Pap smear method; to study the distribution of cervical lesions and to correlate cytology with histopathology wherever available. MATERIALS AND METHODS: The study was conducted at pathology department of GMC, HALDWANI. It comprised of 324 cases of PAP smear of women with complaints pertaining to cervix over a period of two years.. PAP smear results were reported according to 'The Bethesda system' (TBS), followed by cervical biopsy and surgically resected specimens, wherever available. RESULTS: Total 324 cases were evaluated on pap smear cytology. The most of the cases comprised of peri and post menopausal age group (141women,43.52%) while only 16 women (4.96%) are over 65 years. Most common symptom was lower abdominal pain (100 cases; 30.87%). The cervical lesions were categorized as: 14 (4.32%) cases unsatisfactory, 231 (71.30%) cases benign /inflammatory, 60 (18.52%) cases normal, 15 (4.63%) cases of pre-malignant and 4 (1.23%) cases of malignant category. On histopathological examination, maximum 59 (68.61%) cases were inflammatory, 7 (8.14%) cases were pre-malignant and 20 (23.25%) cases were malignant. CONCLUSION: Our study concluded that the pap smear examination is a useful technique to find the cause of cervical lesions. It is easy to perform, minimally invasive, outdoor procedure that gives quick results and should be followed at all the centers.

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A cyto-histopathological correlation study of lesions of uterine cervix

Cited by 2 publications

References 0 publications

Clinical, Cytological and Histopathological Correlation in Lesions of Uterine Cervix

Clinical, Cytological and Histopathological Correlation in Lesions of Uterine Cervix

Profile of utero-cervical lesions in peri- & post-menopausal women in Kumaon Region of Uttarakhand: An Institutional study

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