The main challenge in the implementation of longlasting vibration monitoring systems is to tackle the constantly evolving complexity of modern 'mesoscale' structures. Thus, the design of energy aware solutions is promoted for the joint optimization of data sampling rates, on-board storage requirements, and communication data payloads.In this context, the present work explores the feasibility of the rakeness-based compressed sensing (Rak-CS) approach to tune the sensing mechanism on the second-order statistics of measured data. In particular, a novel model-assisted variant (MRak-CS) is proposed, which is built on a synthetic derivation of the spectral profile of the structure by pivoting on numerical priors. Moreover, a signal-adapted sparsity basis relying on the Wavelet Packet Transform operator is conceived, which aims at maximizing the signal sparsity while allowing for a precise timefrequency localization.The adopted solutions were tested with experiments performed on a sensorized pinned-pinned steel beam. Results prove that the rakeness-based compression strategies are superior to conventional eigenvalue approaches and to standard CS methods. The achieved compression ratio is equal to 7 and the quality of the reconstructed structural parameters is preserved even in presence of defective configurations.