1998
DOI: 10.1006/geno.1998.5231
|View full text |Cite
|
Sign up to set email alerts
|

A Detailed Physical and Transcriptional Map of the Region of Chromosome 20 That Is Deleted in Myeloproliferative Disorders and Refinement of the Common Deleted Region

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
4
1

Citation Types

1
54
2

Year Published

1999
1999
2010
2010

Publication Types

Select...
6

Relationship

1
5

Authors

Journals

citations
Cited by 44 publications
(57 citation statements)
references
References 85 publications
1
54
2
Order By: Relevance
“…In each patient, signals from both LSI 20q13 and CEP20 but not LSI D20S108 were observed on the deleted chromosome 20 con®rming the presence of an interstitial deletion (summarized in Figure 3). Metaphases from each patient were then hybridized with PACs mapping at the boundaries of the known MPD and MDS/AML CDRs ± D20S107 which lies at the proximal boundary of the CDRs and D20S176 which lies telomeric of the distal boundary of the CDRs (Bench et al, 1998a;Wang et al, 1998).…”
Section: Deletion Mapping Analysismentioning
confidence: 99%
See 4 more Smart Citations
“…In each patient, signals from both LSI 20q13 and CEP20 but not LSI D20S108 were observed on the deleted chromosome 20 con®rming the presence of an interstitial deletion (summarized in Figure 3). Metaphases from each patient were then hybridized with PACs mapping at the boundaries of the known MPD and MDS/AML CDRs ± D20S107 which lies at the proximal boundary of the CDRs and D20S176 which lies telomeric of the distal boundary of the CDRs (Bench et al, 1998a;Wang et al, 1998).…”
Section: Deletion Mapping Analysismentioning
confidence: 99%
“…Unfortunately systematic microsatellite PCR analysis of an 11 Mb region spanning the CDRs did not reveal any small deletions in patients with PV and a normal karyotype (Asimakopoulos et al, 1996a). Similarly, in patients with a visible 20q deletion, no small deletions have been detected on the normal chromosome 20 homologue (Bench et al, 1998a). In both these studies, the microsatellite markers were separated by an average of 500 ± 1000 kb and so it is possible that deletions smaller than this may have been missed.…”
Section: Introductionmentioning
confidence: 95%
See 3 more Smart Citations