A dimeric triterpene-glycoside fromRubus coreanus

A dimeric triterpenoid glycoside and flavonoid glycosides with free radical-scavenging activity isolated from Rubus rigidus var. camerunensis

“…By comparison of spectral data obtained by mainly 500 MHz 1D-and 2D-NMR techniques ( 1 H, 13 C, DEPT, COSY, HMBC, HMQC and NOESY) with literature data, compounds 1-8 was identified: kaempferol-3-O-(2′′-E-p-coumaroylglucopyranoside) (1) (Liu et al, 1999), kaempferol-3-O-β-D-glucopyranoside (astragalin, 2) (Singab et al, 2005), kaempferol-3-O-α-L-arabinofuranoside (juglanin, 3) (Olszewska, 2005), quercetin-3-O-β-D-glucopyranoside (isoquercitrin, 4) (Singab et al, 2005), pelargonidin-3-O-β-D-glucopyranoside (callistephin, 5) (Kuskoski et al, 2003), 2α,3β,19α, 23-tetrahydroxyurs-12-ene-28-O-β-D-glucopyranosyl ester (niga-ichigoside F 1, 6) (Seto et al, 1984), 2α,3β,19α -trihydroxyurs-12-ene-23-carboxyl-28-O-β-D-glucopy-ranosyl ester (suavissimoside R 1, 7) (Gao et al, 1985) and coreanoside F 1 (8) (Ohtani et al, 1990) (Fig. 1).…”

“…camerunensis is a plant currently used in Cameroonian folk medicine for the treatment of respiratory and cardiovascular ailments which are highly associated to oxidative stress. It has been reported that the Rosaceae family and more precisely the genus Rubus is a reputed source of polyhydroxylated triterpenoids and dimeric triterpene glucosides (Ohtani et al, 1990;Wang et al, 2000). Moreover, they have been found to contain flavonoids and polyphenolic derivatives (Häkkinen et al, 1999;Hussein et al, 2003).…”

Ursolic acid analogues: non-phenolic functional food components in Jamaican raspberry fruits

“…This is in contrast to the little research that has been undertaken on the phytochemistry of the fruits. Of the compounds isolated from this genus, triterpenoids of the ursane and oleanane types are among those reported (Ohtani et al, 1990;Zhou, 1992). The methanolic extract of the aerial parts of R. rosifolius was shown to possess strong analgesic properties, the active principle being identified as 28-methoxytormentic acid (Kanegusuku et al, 2007).…”

“…Also called the West Indian raspberry, it is one of the many fruit-bearing plant species in Jamaica that is under utilized, being known and eaten by only a minority of the populace. Much of the work done on the Rubus genus to date has been focused on either the anthocyanin content of the fruits or the phytochemistry of the aerial parts (Byamukama et al, 2005;Deighton et al, 2000;Ohtani et al, 1990;Zhou, 1992). This is in contrast to the little research that has been undertaken on the phytochemistry of the fruits.…”

Two novel glycosyl cinnamic and benzoic acids from korean black raspberry (Rubus coreanus) wine

“…In addition, many studies have reported that the fruit exerts various biological effects including anticancer (3), antimicrobial (4), antioxidant (5-7), hepatitis B virus inhibitory (8), antinociceptive, and anti-inflammatory (9) activities. Moreover, the bioactive components of KBR fruit including anthocyanins (10,11), triterpenoids (12,13), flavonoids (6,7), and tannins (14,15) have been identified. KBR fruit has been used in various processed foods in Korea (16).…”