A disposable biosensor for noninvasive diabetic diagnosis rest on the Au/TiO2 nano-composite intensified electrochemiluminescence

Yu, Liang; Wei, Xiuhua; Chen, Fang; Tu, Yifeng

doi:10.1016/j.electacta.2016.06.034

Cited by 32 publications

(12 citation statements)

References 48 publications

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“…To investigate the performance of the sensor when directly integrated with biological tissue, the sensor was transferred onto the surface of a bovine tooth (Figure f, inset). Future work is required to demonstrate the application of this concept for the measurement of salivary metabolites such as glucose and caffeine as well as to further decrease the size of the antenna to a size suitable for integration on human teeth.…”

Section: Body Fluid Biomarkers and Sensorsmentioning

confidence: 99%

Wearable and Miniaturized Sensor Technologies for Personalized and Preventive Medicine

Tricoli

Nasiri

2017

Adv Funct Materials

289

204

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The unprecedented medical achievements of the last century have dramatically improved our quality of life. Today, the high cost of many healthcare approaches challenges their long‐term financial sustainability and translation to a global scale. The convergence of wearable electronics, miniaturized sensor technologies, and big data analysis provides novel opportunities to improve the quality of healthcare while decreasing costs by the very early stage detection and prevention of fatal and chronic diseases. Here, some exciting achievements, emerging technologies, and standing challenges for the development of non‐invasive personalized and preventive medicine devices are discussed. The engineering of wire‐ and power‐less ultra‐thin sensors on wearable biocompatible materials that can be placed on the skin, pupil, and teeth is reviewed, focusing on common solutions and current limitations. The integration and development of sophisticated sensing nanomaterials are presented with respect to their performance, showing exemplary implementations for the detection of ultra‐low concentrations of biomarkers in complex mixtures such as the human sweat and breath. This review is concluded by summarizing achievements and standing challenges with the aim to provide directions for future research in miniaturized medical sensor technologies.

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Section: Body Fluid Biomarkers and Sensorsmentioning

confidence: 99%

Wearable and Miniaturized Sensor Technologies for Personalized and Preventive Medicine

Tricoli

Nasiri

2017

Adv Funct Materials

289

204

View full text Add to dashboard Cite

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“…The detection of glucose in real human serum samples demonstrated acceptable sensitivity and selectivity. Yu, L. et al [ 109 ] developed another disposable glucose ECL biosensor using Au and TiO 2 nano-composite. GOx was cross-linked with BSA thanks to the use of glutaraldehyde, while Nafion is used for enzyme immobilization on the ITO surface.…”

Section: Ecl Enzymatic Biosensorsmentioning

confidence: 99%

Electrochemiluminescence Biosensors Using Screen-Printed Electrodes

et al. 2020

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Electrogenerated chemiluminescence (also called electrochemiluminescence (ECL)) has become a great focus of attention in different fields of analysis, mainly as a consequence of the potential remarkably high sensitivity and wide dynamic range. In the particular case of sensing applications, ECL biosensor unites the benefits of the high selectivity of biological recognition elements and the high sensitivity of ECL analysis methods. Hence, it is a powerful analytical device for sensitive detection of different analytes of interest in medical prognosis and diagnosis, food control and environment. These wide range of applications are increased by the introduction of screen-printed electrodes (SPEs). Disposable SPE-based biosensors cover the need to perform in-situ measurements with portable devices quickly and accurately. In this review, we sum up the latest biosensing applications and current progress on ECL bioanalysis combined with disposable SPEs in the field of bio affinity ECL sensors including immunosensors, DNA analysis and catalytic ECL sensors. Furthermore, the integration of nanomaterials with particular physical and chemical properties in the ECL biosensing systems has improved tremendously their sensitivity and overall performance, being one of the most appropriates research fields for the development of highly sensitive ECL biosensor devices.

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“…‐ Therefore, considerable attention has been devoted in studies of TiO 2 nanomaterial and their applications in ECL. Yu et al reported a novel enzymatic ECL biosensor based on the sensitization from Au/TiO 2 nanocomposite . The Au/TiO 2 nanocomposite, which was deposited on the surface of ITO, significantly enhanced the ECL signal, and a sensitive response toward H 2 O 2 was observed.…”

Section: Nanostructured Metal Oxidesmentioning

confidence: 99%

Nanomaterials in Electrochemiluminescence Sensors

Sun

Liang

2017

ChemElectroChem

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Electrochemiluminescence (ECL) is a means of converting electrical energy into radiative energy. With combined advantages of chemiluminescence and electrochemical control, an interest in ECL has grown rapidly and is broadly applied in biological analysis. Recently, nanomaterials have been widely applied in the vast majority of ECL studies to remarkably amplify signals, owing to their excellent conductivity, large surface area, and sometimes catalytic activity. Herein, we present a Review article on novel nanomaterials in ECL sensors. We introduce the main types of nanomaterials and their physical, chemical, and biological properties along with applications in different ECL sensors with respect to the corresponding functions they serve. A major focus is placed upon numerous research strategies for addressing the signal amplification with nanomaterials in ECL. Lastly, a perspective on the challenges and opportunities of this emerging field is given.

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A disposable biosensor for noninvasive diabetic diagnosis rest on the Au/TiO2 nano-composite intensified electrochemiluminescence

Cited by 32 publications

References 48 publications

Wearable and Miniaturized Sensor Technologies for Personalized and Preventive Medicine

Wearable and Miniaturized Sensor Technologies for Personalized and Preventive Medicine

Electrochemiluminescence Biosensors Using Screen-Printed Electrodes

Nanomaterials in Electrochemiluminescence Sensors

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