A distinctive skin rash associated with coronavirus disease 2019?

Abstract

COVID-19 and Cutaneous manifestations Dear Editor We found that the article on 'Cutaneous manifestations in COVID-19: a first perspective' is very interesting. 1 Recalcati noted that 20.4% of the patients have cutaneous problem and mentioned that this is the first report on this clinical aspect of COVID-19. The wide spectrum of dermatological problem in patients with COVID-19 is an interesting clinical data. Based on our experiences in Thailand, the second country that COVID-19 occurred, almost all patients have no significant dermatological presentation. In fact, in caring patient with severe illness, skin disorder might not be completely investigated. The role of dermatologist in caring COVID-19 patients might be overlooked. An important question is whether the dermatological problem in COVID-19 has any clinical impact on diagnosis and treatment of disease. Some skin disorders in COVID-19 might result in missed diagnosis. For example, the petechiae rash might result in incorrect diagnosis as dengue.

Skin manifestations of COVID-19

“…For example, a 64-year-old woman in France with COVID-19 who developed a rash consistent with Symmetrical Drug-Related Intertriginous and Flexural Exanthema (SDRIFE) 4 days after she became febrile was recently reported. 5 Although SDRIFE is usually a medicationinduced eruption, the authors were unable to attribute this case to a culprit medication. Additionally, Joob and colleagues 11 reported a petechial rash in a COVID-19 patient that mimicked the cutaneous eruption seen in Dengue fever.…”

“…■ VESICULAR ERUPTIONS Varicella-like vesicular eruptions have been described in COVID-19 patients. 5,6 Italian researchers described 22 patients with scattered or diffuse varicella-like vesiculopapular eruptions, representing the largest cohort of COVID-19 patients published thus far with similar cutaneous eruptions. 6 The authors concluded that these vesiculopapular eruptions were specifi c to COVID-19, stressing that no patient in their cohort had been exposed to new medications in the 15 days before eruption onset.…”

Pityriasis rosea as a cutaneous manifestation of COVID‐19 infection

“…Dear editor, Cutaneous manifestation has been reported in 0.2% of patients infected by COVID-19 in China [1], and 18 out of 88 patients from Italy [2]. The most commonly reported features are exanthomatous rash, urticaria, chickenpox like vesicles, petechiae, and acute hemorrhagic edema of infancy [3][4][5].…”

SARS‐CoV‐2 infection presenting as a febrile rash

“…For instance, some patients with Covid-19 associated cutaneous manifestation have been reported, but there is a lack of iconographic and histological documentation. [3][4][5][6][7][8][9] Herein, we describe a febrile rash as the only clinical manifestation of SARS-CoV-2 infection in a patient free from pulmonary symptoms. Despite normal chest radiograph on admission, a chest CT scan showed bilateral and peripheral ground-glass and consolidative pulmonary opacities, highly suggestive of SARS-CoV-2 infection.…”