A dosimetric comparative study between conformal and intensity modulated radiation therapy in the treatment of primary nasopharyngeal carcinomas: the Egyptian experience

Dosimetric and radiobiological comparison in head-and-neck radiotherapy using JO-IMRT and 3D-CRT

“…For 3D-CRT and JO-IMRT, the mean dosage to the parotid gland was 56 Gy and 27 Gy, respectively. Our findings were in agreement with those of El-Ghoneimy et al ( El-Ghoneimy et al, 2012 ) and Puzhakkal et al ( Puzhakkal et al, 2016 ). Fig.…”

Study of dosimetric indices and dose constraints to critical organs for head and neck tumours treated with inverse planned simultaneous integrated boost intensity-modulated radiotherapy

“…[39][40] Sparing of these glands is strongly recommended and is dependant on their complete or partial inclusion in the target volume. 1 A study by El-Ghoneimy et al, 16 reported a mean dose of 24•28 Gy to parotid glands, in their analysis of treatment plans, revealed that a mean dose to bilateral parotid glands, for 47% cases do not fall within tolerance limits, which was due to the complex anatomy and large number of OARs in the vicinity of tumour site making planning of H&N cancer a challenging task. As per RTOG H0225 protocol, 41 minor deviation was observed for TD to parotid glands.…”

“…43 A literature survey highlights the importance of shrinking field IMRT technique over threedimensional conformal radiotherapy and RapidArc techniques. 15,16 Based on published data it was observed that SIB not only provides a high conformal dose distribution and better coverage to the target volume but also protect susceptible organs. [45][46][47] Doses to low risk PTV and boosted high risk PTV are delivered in a single plan with different doses per fraction in contrast to sequential boost (SEQ) technique.…”

“…TDs given in Table 1 are based on a comprehensive review of the literature. 1,[11][12][13][14][15][16][17][18] Dose constraints and priorities of organs for treatment planning are in accordance with Danish Head and Neck Cancer Group (DAHANCA) (13)(14) as represented in Table 1.…”