A dosimetric comparison of Xoft Axxent Electronic Brachytherapy and iridium-192 high-dose-rate brachytherapy in the treatment of endometrial cancer

New Technology in High-Dose-Rate Brachytherapy with Surface Applicators for Non-Melanoma Skin Cancer Treatment: Electronic Miniature X-Ray Brachytherapy

“…Overall, it has been shown that Xoft miniature x-ray source can produce comparable dose distribution for intracavitory brachytherapy treatment compared to 192 Ir source [26][27][28] . One major concern is the relatively more rapid dose fall off with distance in tissue compared to 192 Ir source, which results in a higher surface dose near the MammoSite balloon applicator for APBI treatment or the Vaginal cylinder applicator for endometrial treatment.…”

Comparison of Axxent-Xoft,192Ir and60Co high-dose-rate brachytherapy sources for image-guided brachytherapy treatment planning for cervical cancer

“…The results were in good agreement and consistent with what has been published in the literature for the Xoft-EBS source. 7,8 OARs including rectum, bladder, sigmoid and small bowel were all individually contoured. The Foley catheter balloon with the contrast media was also contoured to represent the bladder.…”

“…7 This electronic brachytherapy system has been investigated by numerous authors for brachytherapy applications such as accelerated partial breast irradiation, surface treatments for skin cancers and endometrial cancer brachytherapy treatments but not for tandem and ovoids (T&O) applicators. [7][8][9][10] The objective of this study was to evaluate the dosimetry of T&O treatment plans generated using the Axxent-Xoft EBS. These plans were then compared with plans generated with the 192 Ir and 60 Co HDR radioactive sources.…”

Electronic brachytherapy—current status and future directions

“…Conversely, doses to surrounding organs at risk are lower, because of the relatively rapid dose fall off. 25,26 Dosimetric characteristics have also been described for endometrial, 27 surface 28 and endocavitary applicators.…”