A Double-blind, Parallel-group, Placebo-controlled, Dose-ranging Study of Intravenous Granisetron in the Prevention of Postoperative Nausea and Vomiting

Diemunsch, Pierre; Wilson, James L; Chitour, Kamil; Patterson, J.E.; Kong, K. L.

doi:10.1097/00000542-199409001-01280

Cited by 7 publications

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“…Studien über 2 und 0,5 mg sind zur Zeit noch nicht abgeschlossen. Granisetron hat sich in einer Einzeldosis von lediglich 1 mg bereits als prophylaktisch wirksam erwiesen, wobei 3 mg nicht effektiver waren (35). Für Dolasetron ist eine Dosis von 25mg i.v.…”

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Prophylaxe und Behandlung von postoperativer Übelkeit und Erbrechen mit 5-HT₃-Rezeptorenblockern

Alon

Bíró²

1996

Anästhesiol Intensivmed Notfallmed Schmerzther

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Since there continues to be a high incidence of postoperative nausea and vomiting associated with many types of surgery, and the standard antiemetics often do not achieve satisfactory results, there have been attempts to use the 5-HT3 antagonists. This group of substances is relatively new, but has already been used successfully as an antiemetic during chemotherapy. To date, results are on hand for four different 5-HT3 receptor blockers: ondansetron, tropisetron, granisetron and dolasetron. Applied intravenously, all four have been effective both in prophylaxis and also as therapy for postoperative emesis. Except for ondansetron, there is so far no definitely clear knowledge about the lowest possible effective dosage. The entire group is well tolerated: only occasional and minor side effects have been reported. Even though not all the hopes originally set in the 5-HT3 group of antagonists have been fulfilled, progress has nevertheless been achieved. Especially noteworthy points are a positive cost-effectiveness relationship of these drugs and their appropriate use in case of the proper indications.

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Section: Dosierungunclassified

Prophylaxe und Behandlung von postoperativer Übelkeit und Erbrechen mit 5-HT₃-Rezeptorenblockern

Alon

Bíró²

1996

Anästhesiol Intensivmed Notfallmed Schmerzther

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The Role of the Laryngeal Mask in Clinical Practice

Brain¹,

Brimacombe²

1996

Anaesthesia, Pain, Intensive Care and Emergency Medicine — A.P.I.C.E.

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The advantages of the LMA over the tracheal tube or facemask: a meta-analysis

1995

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The advantages of the LMA over the tracheal tube or facemask: a meta-analysis The laryngeal mask airway (LMA) has gained widespread acceptance as a general purpose airway with worldwide usage estimated at over ten million patients by 1993. l The popularity of the device for routine use stems from its perceived benefits for the patient and anaesthetist over traditional forms of airway management. Prospective surveys have shown the overall success rate for the technique to be high and the complication rate low, 2-5 but it has been suggested that there is a lack of CAN J ANAESTH 1995 / 42:1 i / pp 1017-23 A meta-analysis was performed on randomisedprospective trials comparing the laryngeal mask airway (LMA) with other forms of airway management to determine if the LMA offered any advantages over the tracheal tube (TT) or facemask (FM

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A Double-blind, Parallel-group, Placebo-controlled, Dose-ranging Study of Intravenous Granisetron in the Prevention of Postoperative Nausea and Vomiting

Cited by 7 publications

References 0 publications

Prophylaxe und Behandlung von postoperativer Übelkeit und Erbrechen mit 5-HT₃-Rezeptorenblockern

Prophylaxe und Behandlung von postoperativer Übelkeit und Erbrechen mit 5-HT₃-Rezeptorenblockern

The Role of the Laryngeal Mask in Clinical Practice

The advantages of the LMA over the tracheal tube or facemask: a meta-analysis

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A Double-blind, Parallel-group, Placebo-controlled, Dose-ranging Study of Intravenous Granisetron in the Prevention of Postoperative Nausea and Vomiting

Cited by 7 publications

References 0 publications

Prophylaxe und Behandlung von postoperativer Übelkeit und Erbrechen mit 5-HT3-Rezeptorenblockern

Prophylaxe und Behandlung von postoperativer Übelkeit und Erbrechen mit 5-HT3-Rezeptorenblockern

The Role of the Laryngeal Mask in Clinical Practice

The advantages of the LMA over the tracheal tube or facemask: a meta-analysis

Contact Info

Product

Resources

About

Prophylaxe und Behandlung von postoperativer Übelkeit und Erbrechen mit 5-HT₃-Rezeptorenblockern

Prophylaxe und Behandlung von postoperativer Übelkeit und Erbrechen mit 5-HT₃-Rezeptorenblockern