A dynamic approach to identifying desired physiological phases for cardiac imaging using multislice spiral CT

Vembar, Mani; García, Mario J.; Heuscher, Dominic J.; Haberl, Ralph; Matthews, Dennis L; Böhme, Georg-Eike; Greenberg, Neil L.

doi:10.1118/1.1582812

Cited by 107 publications

(70 citation statements)

References 18 publications

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“…In fact, ECG‐gated spiral CT using multislice scanners has made it possible to scan the entire heart in a single breath hold, while continuous data acquisition makes it possible to reconstruct the multiple phases of the cardiac cycle. ( 18 ) …”

Section: Discussionmentioning

confidence: 99%

Comparative evaluation of image quality from three CT simulation scanners

McCann

Alasti

2004

J Applied Clin Med Phys

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Today, radiation therapy (RT) is moving toward increased radiation dose to the tumor as a result of 3D conformal RT (3DCRT) and intensity‐modulated RT (IMRT), which have been made possible by advances in volumetric‐based image planning with digital imaging systems such as computed tomography (CT). Treatment planning for such RT requires superior CT image quality. Our goal in this study was to evaluate and to compare the image quality of three unique CT simulation scanners available at our center for both single‐ and multiple‐slice helical scanners. These scanners included a conventional 70‐cm bore single‐slice scanner (Philips Medical Systems), a large 85‐cm bore single‐slice scanner (Philips Medical Systems), and a 70‐cm bore multislice scanner (GE Medical Systems). Image quality was evaluated in terms of image noise, low‐contrast detectability (LCD), limiting spatial resolution (modulation transfer function), and slice thickness accuracy in accordance with guidelines set out by the AAPM. A commercially available Catphan® phantom was used to characterize image quality for both axial and helical modes of scanning. We found that image quality was generally comparable for all scanners. Limiting spatial resolution and slice thickness accuracy were comparable for all three scanners for both scanning modes. The multislice unit was superior in terms of noise content, resulting in improved visualization of small, low‐contrast objects, which is of significant clinical importance, particularly for soft tissue delineation. In addition, the multislice unit optimizes volume coverage speed and longitudinal resolution without compromising image quality, a significant advantage for the radiation oncology environment.PACS numbers: 87.57.Ce, 87.59.Fm, 87.57.Nk

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Section: Discussionmentioning

confidence: 99%

Comparative evaluation of image quality from three CT simulation scanners

McCann

Alasti

2004

J Applied Clin Med Phys

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“…Multiple imaging modalities, including electron beam CT (EBCT) (14), multislice CT (15) and bi-plane angiography (13) have all demonstrated that the RCA displays both the highest speed among the coronaries as well as the greatest range of motion. Therefore, significant motion artifacts are expected when imaging the RCA (Figure 2).…”

Section: Discussionmentioning

confidence: 99%

“…(12)). In this work we have simulated a heart rate of 60 beats per minute, and the peak vessel velocity is nearly 8 cm/s (within the range of measured coronary velocities (13)(14)(15)). Several positions within the cardiac cycle have been labeled in Figure 1 for reference as they will be referred to when the reconstruction results are presented.…”

Section: Controlled Motion Phantommentioning

confidence: 99%

Temporally Targeted Imaging Method Applied to ECG-Gated Computed Tomography

Nett¹,

Leng²,

Zambelli³

et al. 2008

Academic Radiology

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Rationale and Objectives-Existing cardiac imaging methods do not allow for improved temporal resolution when considering a targeted region of interest (ROI). The imaging method presented here enables improved temporal resolution for ROI imaging (namely, a reconstruction volume smaller than the complete field of view). Clinically, temporally targeted reconstruction would not change the primary means of reconstructing and evaluating images, but rather would enable the adjunct technique of ROI imaging, with improved temporal resolution compared with standard reconstruction (~20% smaller temporal scan window). In gated cardiac CT scans improved temporal resolution directly translates into a reduction in motion artifacts for rapidly moving objects such as the coronary arteries.Materials and Methods-Retrospectively electrocardiogram gated coronary angiography data from a 64-slice CT system were utilized. A motion phantom simulating the motion profile of a coronary artery was constructed and scanned. Additionally, an in vivo study was performed using a porcine model. Comparisons between the new reconstruction technique and the standard reconstruction are given for an ROI centered on the right coronary artery, and a pulmonary ROI.Results-In both a well controlled motion model and a porcine model results show a decrease in motion induced artifacts including motion blur and streak artifacts from contrast enhanced vessels within the targeted ROIs, as assessed through both qualitative and quantitative observations. Conclusion-Temporally targeted reconstruction techniques demonstrate the potential to reduce motion artifacts in coronary CT. Further study is warranted to demonstrate the conditions under which this technique will offer direct clinical utility. Improvement in temporal resolution for gated cardiac scans has implications for improving: contrast enhanced CT angiography, calcium scoring, and assessment of the pulmonary anatomy.

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“…For the selection of the optimal cardiac phase, each axial image of every 5% in the cardiac phase was reconstructed at 3 different levels (ostium of the right coronary artery, the acute marginal bifurcation, and the obtuse marginal bifurcation), which have been reported to show marked movement compared with other areas. 12 The image of the mid-diastolic phase was judged by visual inspection to be the most excellent in all the present patients.…”

Section: Scaning Protocol and Image Reconstructionmentioning

confidence: 99%

Evaluation of Coronary Artery Lumen Diameter With 16-Slice Multidetector-Row Computed Tomography

Yamada

Jinzaki

Kuribayashi

et al. 2005

Circ J

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ultidetector-row computed tomography (MDCT) has been recently introduced as a non-invasive method of evaluating the coronary arteries, and has been used successfully in the clinical field. 1-8 Coronary arteries measuring 1.5 mm or larger in lumen diameter are usually evaluated in studies of coronary artery stenosis using 16-slice computed tomography (CT), 9-10 but to our knowledge, there has not been a study of the lumen diameter of each coronary artery segment, classified according to the American Heart Association Committee Report, 11 using 16-slice MDCT and thus, how much of the coronary artery segments are generally assessable by 16-slice MDCT is unknown. Methods Study PopulationFrom May through August 2003, 57 patients with suspected coronary artery disease underwent MDCT and of these, 21 were diagnosed as having no significant stenosis in the coronary artery based on the finding of MDCT. Excluding 1 patient with extreme right-dominance, 20 patients (10 males, 10 females; mean age, 57±6.9 years (range: 49-65 years)) comprised our study population. Heart rate ranged from 52 to 76 beats/min and the change in heart rate was less than 5 beats/min. Scaning Protocol and Image ReconstructionWe used 16-slice MDCT (Light Speed ultra16: GE Healthcare, WI, USA) and after obtaining an unenhanced scan of the whole heart, sublingual nitroglycerin (0.3 mg) was administered.The test injection method was used to determine the delay time of the main scanning. The dynamic monitoring scans were positioned at the level of the ascending aorta. Each monitoring scan was acquired every 2 s. Acquisition of the dynamic monitoring scans (120 kV, 20 mA) started 10 s after the beginning of the injection of intravenous contrast media (20 ml at a rate of 3 ml/s; Iopamiron 370: Nihon Schering Co, Ltd, Japan) and saline chaser of 20 ml. An enhancement curve was drawn by placing the region of interest on the ascending aorta at the coronary artery ostium level to indicate the time needed to reach the peak of maximum enhancement for the test bolus. The time to peak enhancement for the test bolus injection plus 2 s was the delay applied for the main scanning.In the main scanning, contrast material and saline chaser of 20 ml was injected at a rate of 3 ml/s. The contrast material volume was 3 (injection rate) × scanning time. The main scanning parameters were: tube voltage of 120 kV, tube current of 350-380 mA, gantry speed of 0.5 s/rotation, detector collimation of 16×0.625 mm, and a pitch of 0.275-0.3, scanning direction craniocaudal. The field of view reconstructed axial image was 200 mm with a 512×512 matrix, and the kernel used was standard.The raw data of the main scanning were reconstructed using half reconstruction for the patients with a heart rate less than 60 beats/min, and the multisector reconstruction for the patients with a heart rate of more than 60 beats/min respectively. For the selection of the optimal cardiac phase, Evaluation of Coronary Artery Lumen Diameter With 16-Slice Multidetector-Row Computed TomographyMinoru Yamad...

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A dynamic approach to identifying desired physiological phases for cardiac imaging using multislice spiral CT

Cited by 107 publications

References 18 publications

Comparative evaluation of image quality from three CT simulation scanners

Comparative evaluation of image quality from three CT simulation scanners

Temporally Targeted Imaging Method Applied to ECG-Gated Computed Tomography

Evaluation of Coronary Artery Lumen Diameter With 16-Slice Multidetector-Row Computed Tomography

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