In order to break the bottleneck of the human capital stock restricting local economic growth in the typical western regions with backward national economic development, a research on the analysis of the impact of human resources on the economic development of ethnic regions based on data mining is proposed. On the basis of systematically reviewing the current situation and the theoretical basis of the relationship between human capital and economic growth, the method of combining normative research and empirical research is adopted, and the theories of macroeconomics, development economics, and regional economics are synthesized. In the research, the human capital and economic development in a certain western region are analyzed by establishing an econometric model. The results show that the average value of each year is taken as the inspection index, and the contribution rate is 0.0012, which shows that the contribution of human capital stock in economic growth is very small, indicating that physical capital stock is still the main driving force for local economic development. It is concluded that the research provides some relevant recommendations for human capital development to achieve sustainable local economic development.