This chapter explores the potential of combining two useful ecologicaleconomic methods: input-output analysis and multi-criteria decision aid. By doing so, it assesses the sustainability of investment in various economic sectors, with the aim of minimising resource use and generation of emissions. The UK case is taken for the purpose of illustration, and (given the availability of the necessary data) this methodology might be applied in countries with various economic structures and specialisations. An environmentally extended static 123-sector UK input-output model is used, linking a range of physical fl ows (domestic extraction, use of water, and emissions of CO 2 , CH 4 , NO x ) with the economic structure of the UK. A range of environmentally adjusted forward and backward linkage coeffi cients has been developed, adjusted according to fi nal demand, domestic extraction, publicly supplied and directly abstracted water, and emissions of CO 2 and NO x . The data on the fi nal demand adjusted and environmentally adjusted forward and backward linkage coeffi cients were used in a multi-criteria decision-aid assessment, employing a NAIADE method in three different sustainability settings. The assessment was constructed in such a way that each sector of the UK economy was assessed by means of a panel of sustainability criteria, maximising economic effects and minimising environmental effects. This type of multi-criteria analysis, could prove to be a valuable basis for similar studies, especially in the developing world, where trade-offs between economic development and environmental protection have been the subject of considerable debate.