A facile strategy for the synthesis of a NaREF₄-gold nanocomposite as a dual-modal bioimaging agent

Abstract

A UCNP&Au@SiO2 nanocomposite synthesized by in situ reduction of HAuCl4 as a dual modality imaging agent.

Noninvasive and real-time pharmacokinetics imaging of polymeric nanoagents in the thoracoepigastric vein networks of living mice

“…Regarding noninvasive visualization of the TVs of small model animals, fluorescence bioimaging has been shown to be advantageous in its high spatiotemporal resolutions. 53,54 Particularly, the recent advances in synthetic nanophosphors capable of luminescence emission in the second near-infrared region (NIR-II, 1000 to 1400 nm), such as single-wall carbon nanotubes, 55 inorganic quantum dots, 56 and rare earth doped upconversion nanoparticles, 57,58 provide new opportunities for real-time bioimaging with a spatial resolution of sub-100 μm and an imaging depth of millimeters. The NIR-II optical bioimaging, besides an impressive penetration depth, can minimize the interference from the autofluorescence of biological tissues, owing to the relatively low light absorption in this spectral window.…”

Core@shell Fe3O4@Mn2+-doped NaYF4:Yb/Tm nanoparticles for triple-modality T1/T2-weighted MRI and NIR-to-NIR upconversion luminescence imaging agents

“…Fourier transform infrared (FTIR) spectra were recorded using a Spectrum One instrument (PerkinElmer) and a KBr pellet in the spectral range of 4000 to 500 cm À1 . 4 :Yb/Tm NPs. Then, the crystal structure and phase purity of the ve samples were examined using XRD, as shown in Fig.…”

“…To evaluate the NIR-to-NIR UCL imaging ability of these C 18 4 :Yb/Tm NPs in the abdomen region for in vivo imaging. The injection depth was about 10 mm (estimated from the needle penetration).…”